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Propofol is one of the most widely used intravenous general anesthetics in clinical practice, mainly due to its rapid onset of action, short half-life period, and high clearance rate. However, propofol is associated with a variety of adverse drug reactions, such as injection site pain, hypotension, respiratory depression, hyperlipidemia, allergies, and propofol infusion syndrome. As a water-soluble prodrug of propofol, fospropofol disodium possesses unique formulation advantages and controllable pharmacological properties, and has been gradually applied in the field of clinical anesthesia. This article aims to systematically review the pharmacological characteristics, clinical research progress, advantages and limitations of fospropofol disodium, and prospect its future application prospects in clinical anesthesia.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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