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Evaluation consideration for clinical research and development for adolescent weight management
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Yuan-hong LI, Tian ZHAO, Yu-ying QI, Jie ZHANG
Chinese Journal of Clinical Pharmacology | 2026, 42(2) : 297 - 300
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Chinese Journal of Clinical Pharmacology | 2026, 42(2): 297-300
Regulatory Science Column
Evaluation consideration for clinical research and development for adolescent weight management
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Yuan-hong LI, Tian ZHAO, Yu-ying QI, Jie ZHANG
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  • Center for Drug Evaluation, National Medical Products Administration, Beijing 100076, China
Published: 2026-01-28 doi: 10.13699/j.cnki.1001-6821.2026.02.024
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Currently, there are no approved adolescent weight management drugs in China, and there is a significant unmet medical need for adolescent weight management. With glucagon like peptide-1 receptor agonists (GLP-1 RA) design becoming a hot topic in the research and development of adolescent obesity, the number of communication and applications for clinical application in China has gradually increased. Combined with relevant problems encountered in the evaluation, we discussed the design and evaluation consideration for clinical trials of adolescent weight management, so as to improve the research and development and provide references for researchers.

adolescent  /  weight management  /  glucagon-like peptide-1 receptor agonists  /  clinical research development  /  evaluation consideration
Yuan-hong LI, Tian ZHAO, Yu-ying QI, Jie ZHANG. Evaluation consideration for clinical research and development for adolescent weight management[J]. Chinese Journal of Clinical Pharmacology, 2026 , 42 (2) : 297 -300 . DOI: 10.13699/j.cnki.1001-6821.2026.02.024
Year 2026 volume 42 Issue 2
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doi: 10.13699/j.cnki.1001-6821.2026.02.024
  • Receive Date:2025-12-22
  • Online Date:2026-08-06
  • Published:2026-01-28
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  • Received:2025-12-22
Affiliations
    Center for Drug Evaluation, National Medical Products Administration, Beijing 100076, China
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表12种不同金属材料的力学参数

Family
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Number of
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Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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