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Exploration and practice of digital management for decentralized clinical trials based on internet platform
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Dong-bo WANG1, Lei XU2, Juan FENG3, Wu-lin WEN4, Yan-ru LI1, Xiao-sheng WANG5, Jin TIAN6, Ya-jie JIA1, Qing HAO7, Xiu-li ZHAO1, De-min HAN1
Chinese Journal of Clinical Pharmacology | 2025, 41(23) : 3447 - 3450
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Chinese Journal of Clinical Pharmacology | 2025, 41(23): 3447-3450
• Special Column of Clinical Trials Administration •
Exploration and practice of digital management for decentralized clinical trials based on internet platform
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Dong-bo WANG1, Lei XU2, Juan FENG3, Wu-lin WEN4, Yan-ru LI1, Xiao-sheng WANG5, Jin TIAN6, Ya-jie JIA1, Qing HAO7, Xiu-li ZHAO1, De-min HAN1
Affiliations
  • 1.Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
  • 2.Shandong Provincial Second Hospital, Jinan 048026, Shandong Province, China
  • 3.The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830013, Xinjiang Uyghur Autonomous Region, China
  • 4.Yinchuan First People’s Hospital, Yinchuan 750001, Ningxia Province, China
  • 5.Pingdingshan First People’s Hospital, Pingdingshan 467200, Henan Province, China
  • 6.Huakang Yichu Health Promotion (Beijing) Co., Ltd., Beijing 100102, China
  • 7.National Key Laboratory for Innovation and Transformation of Luobing Theory, Shijiazhuang 050700, Hebei Province, China
Published: 2025-12-17 doi: 10.13699/j.cnki.1001-6821.2025.23.021
Outline
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Objective

Decentralized clinical trials (DCT) have shown a rapid growth trend in recent years due to their advantages such as being geographically unrestricted, enhancing research efficiency, and reducing research costs. The United States has a significant development advantage in this field, with a clear concentration trend. China is still in its infancy in this area, lacking practical experience and summaries. This study takes the "Multicenter Prospective Open Randomized Controlled Clinical Study on the Early Intervention of Lianhua Qingwen Granules in Acute Pharyngitis Patients" as an example, and through the implementation of DCT digital management based on the internet platform, it sorts out and summarizes the key links in conducting DCT, explores the technical aspects and applicable fields of DCT in China, and provides practical references for accelerating the resolution of the bottlenecks in promoting DCT.

decentralized clinical trials  /  internet  /  digital management  /  patient-centered
Dong-bo WANG, Lei XU, Juan FENG, Wu-lin WEN, Yan-ru LI, Xiao-sheng WANG, Jin TIAN, Ya-jie JIA, Qing HAO, Xiu-li ZHAO, De-min HAN. Exploration and practice of digital management for decentralized clinical trials based on internet platform[J]. Chinese Journal of Clinical Pharmacology, 2025 , 41 (23) : 3447 -3450 . DOI: 10.13699/j.cnki.1001-6821.2025.23.021
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Article Info
doi: 10.13699/j.cnki.1001-6821.2025.23.021
  • Receive Date：2025-10-05
  • Online Date：2026-08-05
  • Published：2025-12-17
Article Data
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History
  • Received：2025-10-05
Funding
Affiliations
    1.Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
    2.Shandong Provincial Second Hospital, Jinan 048026, Shandong Province, China
    3.The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830013, Xinjiang Uyghur Autonomous Region, China
    4.Yinchuan First People’s Hospital, Yinchuan 750001, Ningxia Province, China
    5.Pingdingshan First People’s Hospital, Pingdingshan 467200, Henan Province, China
    6.Huakang Yichu Health Promotion (Beijing) Co., Ltd., Beijing 100102, China
    7.National Key Laboratory for Innovation and Transformation of Luobing Theory, Shijiazhuang 050700, Hebei Province, China
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多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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