Hyperuricemia (HUA) is a metabolic disorder characterized by abnormally elevated serum uric acid levels, with a rising prevalence worldwide. The potential hazards of HUA and its precise intervention strategies have emerged as a central focus in clinical medicine research. Current research indicates that HUA is closely associated with various systemic diseases, such as cardiovascular and renal diseases. Its pathogenic mechanisms involve multiple pathways, such as oxidative stress, inflammatory factor activation, and urate crystal deposition. However, the treatment of HUA patients with comorbid cardiovascular or renal diseases—particularly those with asymptomatic hyperuricemia (AH)—remains highly controversial. Existing clinical guidelines show significant regional variations, European and American guidelines favor a conservative monitoring approach, while Asian guidelines advocate for earlier intervention. Therefore, to establish the long-term clinical benefits for HUA patients, there is an urgent need for evidence-based medical support through large-scale prospective cohort studies and randomized controlled trials (RCTs). These studies will provide a more reliable foundation for standardized clinical management.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |