Postmenopausal osteoporosis (PMOP) is a systemic metabolic bone disease characterised by significant bone loss and deterioration of the bone microstructure. Although traditional anti-osteoporosis drugs have been shown to be effective in preventing and treating PMOP, they can also cause various side effects. Traditional Chinese medicine has been used to treat various diseases for many years and is widely used to treat PMOP due to its high tolerability, low toxicity, good efficacy and minimal adverse reactions. This review summarises the mechanisms of action of PMOP and the current state of research on the mechanisms of action of commonly used Chinese medicinal compounds and combinations for treating PMOP. The aim is to provide ideas for the future clinical treatment of PMOP and related basic research.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |