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Recent advancements in Janus kinase (JAK) inhibitors have highlighted their therapeutic potential in autoimmune diseases, yet safety concerns persist. Chinese pharmaceutical companies are advancing selective JAK inhibitor research and development, focusing on trials for rheumatoid arthritis (RA) patients failing biologic disease-modifying antirheumatic drugs (bDMARDs) and exploring superiority/non-inferiority against tumor necrosis factor (TNF) inhibitors. In the future, JAK inhibitors need to be combined with long-term real-world data to expand the applicable population. This article provides important evidence for new drug research and development, regulatory decisions, and rational clinical medication, with the aim of promoting the safer and more effective use of JAK inhibitors in the treatment of autoimmune diseases.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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