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The clinical efficacy of Chinese medicines in the prevention and treatment of endometriosis (EMs) is precise and can work through multiple pathways and targets. However, the complexity of the components of Chinese medicines and the single research method have led to slow progress in this field. With the emergence of high-throughput technologies, the limitations of single targets or pathways in interpreting the "holistic regulation" of TCM have been remedied by identifying genes associated with the pathophysiology of endometriosis. In this review, genomics, transcriptomics, proteomics, metabolomics, and their combinatorial techniques are reviewed to reveal the molecular mechanisms of Chinese herbal medicines in the prevention and treatment of endometriosis. It provides reference ideas for precise and objective revelation of prevention and treatment of EMs, as well as theoretical basis for revealing the mechanism of complex drug intervention in the disease.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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