Chinese Journal of Clinical Pharmacology
|
2025, 41(3): 433-437
• Review •
Research status of the modulation of TRPV1 signaling pathway and related factors by traditional Chinese medicine for the treatment of herpes zoster and postherpetic neuralgia
Full
Xiao-tao XIE
1, Fan-qi NIU
1, Yu-jing PAN
1, Shi-ye HE
1, Si-nong WANG
1, Wen-li ZHOU
2
Affiliations
- 1.School of Clinical Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
- 2.Department of Dermatology, Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
Published: 2025-02-17
doi: 10.13699/j.cnki.1001-6821.2025.03.027
Outline
The transient receptor potential vanilloid subtype 1 (TRPV1) signaling pathway is closely related to herpes zoster (HZ) and postherpetic neuralgia (PHN). Traditional Chinese medicine (TCM) has been involved in regulating the TRPV1 signaling pathway in several ways, and has been used to treat HZ and PHN by modulating the aberrant release of TRPV1-associated neuropeptides and inflammatory factors, and neurogenic inflammatory response, etc. This paper summarizes the mechanism and role of TCM in regulating TRPV1 signaling pathway in the treatment of HZ and PHN in recent years, which will provide new ideas for the treatment of HZ and PHN and drug development.
traditional Chinese medicine
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herpes zoster and postherpetic neuralgia
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transient receptor potential vanilloid subtype 1
/
inflammatory factor
/
neurogenic inflammation of the skin
谢小涛, 牛凡琪, 潘钰晶, 何世烨, 王思农, 周文丽.
中医药调控TRPV1信号通路和相关因子防治带状疱疹及后遗神经痛的研究现状.
中国临床药理学杂志,
2025
, 41
(3)
: 433
-437
.
DOI: 10.13699/j.cnki.1001-6821.2025.03.027
Xiao-tao XIE, Fan-qi NIU, Yu-jing PAN, Shi-ye HE, Si-nong WANG, Wen-li ZHOU.
Research status of the modulation of TRPV1 signaling pathway and related factors by traditional Chinese medicine for the treatment of herpes zoster and postherpetic neuralgia[J].
Chinese Journal of Clinical Pharmacology,
2025
, 41
(3)
: 433
-437
.
DOI: 10.13699/j.cnki.1001-6821.2025.03.027
Year 2025 volume 41 Issue 3
280
74
Cite this Article
BibTeX
Article Info
doi: 10.13699/j.cnki.1001-6821.2025.03.027
- Receive Date:2024-07-29
- Online Date:2026-08-04
- Published:2025-02-17