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Research status of autophagy in the pathogenesis of rheumatoid arthritis
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Wen-xia QI1, Gang WANG2, Yan-feng YAN3, Jie-xiang TIAN2, Tao WANG2, Yong WEI2, Zhan-dong WANG1, Yuan-yuan ZHANG2
Chinese Journal of Clinical Pharmacology | 2025, 41(2) : 264 - 268
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Chinese Journal of Clinical Pharmacology | 2025, 41(2): 264-268
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Research status of autophagy in the pathogenesis of rheumatoid arthritis
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Wen-xia QI1, Gang WANG2, Yan-feng YAN3, Jie-xiang TIAN2, Tao WANG2, Yong WEI2, Zhan-dong WANG1, Yuan-yuan ZHANG2
Affiliations
  • 1.School of Traditional Chinese of Western Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
  • 2.Department of Rheumatology and Orthopedics, Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730020, Gansu Province, China
  • 3.Department of Respiratory and Critical Care Medicine, Fourth Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730060, Gansu Province, China
Published: 2025-01-28 doi: 10.13699/j.cnki.1001-6821.2025.02.023
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With the deepening of molecular biology and cell biology research, the regulatory mechanism of autophagy has been gradually revealed, providing new ideas for the treatment of numerous diseases. Autophagy may be closely related to pathological changes such as apoptosis resistance of fibroblast-like synoviocytes, disturbances in bone metabolic homeostasis, and antigen presentation, the regulation of autophagy homeostasis may be an important approach for the treatment of rheumatoid arthritis (RA). In this paper, we provide a review on the pathological mechanism of autophagy in RA, with a view to providing a theoretical basis for later studies.

rheumatoid arthritis  /  autophagy  /  pathomechanism  /  research status
Wen-xia QI, Gang WANG, Yan-feng YAN, Jie-xiang TIAN, Tao WANG, Yong WEI, Zhan-dong WANG, Yuan-yuan ZHANG. Research status of autophagy in the pathogenesis of rheumatoid arthritis[J]. Chinese Journal of Clinical Pharmacology, 2025 , 41 (2) : 264 -268 . DOI: 10.13699/j.cnki.1001-6821.2025.02.023
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doi: 10.13699/j.cnki.1001-6821.2025.02.023
  • Receive Date：2024-06-17
  • Online Date：2026-08-04
  • Published：2025-01-28
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  • Received：2024-06-17
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Affiliations
    1.School of Traditional Chinese of Western Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
    2.Department of Rheumatology and Orthopedics, Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730020, Gansu Province, China
    3.Department of Respiratory and Critical Care Medicine, Fourth Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730060, Gansu Province, China
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表12种不同金属材料的力学参数
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Family		 属数
Number of
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Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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