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Rheumatoid arthritis (RA) is categorized as "bi zheng" and "li-jiebing" in Chinese medicine. Liver and kidney insufficiency, marrow can not nourish the bones, feel the external evil, long-term accumulation in the body, heat into poison, damage to the qi and blood meridians and collaterals, heat and poison, phlegm, blood stasis and paralysis and the onset of the disease, mixed with the real and the imaginary, difficult to be cured. The Notch signaling pathway has a greater relevance to this disease, and it is involved in various pathological processes such as inflammatory cell infiltration, proliferation of fibroblast-like synoviocytes (FLS), microvascular formation and bone destruction. In this paper, the correlation between Notch signaling pathway and this disease is discussed from the perspective of the combination of Chinese and Western medicine, based on the theory of "XU, DU, YU" of traditional Chinese medicine, with the aim of providing a new way of thinking for the research.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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