Temozolomide capsule is a first-line chemotherapeutic agent for the treatment of glioblastoma and anaplastic astrocytoma. Combined with radiotherapy, it can significantly improve the survival rate of patients, which is of high clinical value. Based on the public information on the websites of National Medical Products Administration, Food and Drug Administration, European Medicines Angecy and Pharmaceuticals and Medical Devices Angecy, the contents of Chineses Pharmacopoeia, United States Pharmacopeia, British Pharmacopeia, and the requirements of The International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use and domestic chemical generic drugs related guidelines, this paper proposed the pharmaceutical research and development concerns of this product, so as to promote the marketing of generic drugs.
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |