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Research status of action of alkaloids in the treatment of rheumatoid arthritis
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Yun LI, Yu-hui WANG, Li LI, Jia-rong MA, Min ZHAO
Chinese Journal of Clinical Pharmacology | 2025, 41(2) : 269 - 273
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Chinese Journal of Clinical Pharmacology | 2025, 41(2): 269-273
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Research status of action of alkaloids in the treatment of rheumatoid arthritis
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Yun LI, Yu-hui WANG, Li LI, Jia-rong MA, Min ZHAO
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  • Gansu Pharmaceutical Industry Innovation Research Institute, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
Published: 2025-01-28 doi: 10.13699/j.cnki.1001-6821.2025.02.024
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Rheumatoid arthritis (RA) is an inflammatory disease mainly associated with polyarthritis. It is mainly due to the joint swelling and joint inflammation caused by immune cells. The alkaloids in traditional Chinese medicine can reduce the level of pro-inflammatory factors and increase the level of anti-inflammatory factors, reduce the joint synovial tissue hyperplasia, inflammatory cell infiltration and new blood vessel formation, inhibit the differentiation of osteoclasts, and then play an anti-RA role. Therefore, the review used the effects and mechanisms of alkaloids for RA to inform the development of new drugs for RA.

alkaloid  /  rheumatoid arthritis  /  inflammation  /  mechanism of action  /  research status
Yun LI, Yu-hui WANG, Li LI, Jia-rong MA, Min ZHAO. Research status of action of alkaloids in the treatment of rheumatoid arthritis[J]. Chinese Journal of Clinical Pharmacology, 2025 , 41 (2) : 269 -273 . DOI: 10.13699/j.cnki.1001-6821.2025.02.024
Year 2025 volume 41 Issue 2
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doi: 10.13699/j.cnki.1001-6821.2025.02.024
  • Receive Date:2024-06-03
  • Online Date:2026-08-04
  • Published:2025-01-28
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  • Received:2024-06-03
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    Gansu Pharmaceutical Industry Innovation Research Institute, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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