Home Journals Articles Updates About
CN
image
收藏切换
Research status of insulin resistance mechanisms and the improvement of insulin resistance by active ingredients of dark plum
收藏切换
Zhen-ni ZHANG1, Wen-fang JIN1, Hu-gang JIANG1, 2, Xin-qiang WANG1, 2, Kai LIU1, 2, Ying-dong LI1, 2, Xin-ke ZHAO1, 2
Chinese Journal of Clinical Pharmacology | 2025, 41(2) : 274 - 278
Less
收藏切换
Chinese Journal of Clinical Pharmacology | 2025, 41(2): 274-278
• Review •
Research status of insulin resistance mechanisms and the improvement of insulin resistance by active ingredients of dark plum
Full
Zhen-ni ZHANG1, Wen-fang JIN1, Hu-gang JIANG1, 2, Xin-qiang WANG1, 2, Kai LIU1, 2, Ying-dong LI1, 2, Xin-ke ZHAO1, 2
Affiliations
  • 1.School of Traditional Chinese and Western Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
  • 2.Department of Cardiology, Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730030, Gansu Province, China
Published: 2025-01-28 doi: 10.13699/j.cnki.1001-6821.2025.02.025
Outline
收藏切换

Dark plum can be used to treat symptoms such as consumptive thirst due to deficiency-heat and chronic cough due to lung deficiency. Its active ingredients have auxiliary effects on lowering blood glucose, antibacterial and anti-inflammatory activities. Insulin resistance is mainly characterized by the weakening of the physiological effects of insulin in the body, with a relatively complex mechanism that can lead to various metabolic-related diseases and seriously affect health. The active ingredients of dark plum can improve insulin resistance by regulating insulin signaling pathways, endoplasmic reticulum stress, antioxidant stress, inflammatory signaling pathways, levels of related inflammatory mediators, and free fatty acid levels. By reviewing the relevant literature on the improvement of insulin resistance by the active ingredients of dark plum, this article summarizes and analyzes its mechanism of action, aiming to provide new ideas and scientific evidence for in-depth research on insulin resistance and the development and application of drugs.

dark plum  /  active ingredient  /  signaling pathway  /  stress response  /  insulin resistance
张珍妮, 靳文芳, 蒋虎刚, 王新强, 刘凯, 李应东, 赵信科. 胰岛素抵抗机制及乌梅活性成分改善胰岛素抵抗的研究现状. 中国临床药理学杂志, 2025 , 41 (2) : 274 -278 . DOI: 10.13699/j.cnki.1001-6821.2025.02.025
Zhen-ni ZHANG, Wen-fang JIN, Hu-gang JIANG, Xin-qiang WANG, Kai LIU, Ying-dong LI, Xin-ke ZHAO. Research status of insulin resistance mechanisms and the improvement of insulin resistance by active ingredients of dark plum[J]. Chinese Journal of Clinical Pharmacology, 2025 , 41 (2) : 274 -278 . DOI: 10.13699/j.cnki.1001-6821.2025.02.025
Appendix
Less
Year 2025 volume 41 Issue 2
408
242
Cite this Article
BibTeX
Article Info
doi: 10.13699/j.cnki.1001-6821.2025.02.025
  • Receive Date：2024-07-20
  • Online Date：2026-08-04
  • Published：2025-01-28
Article Data
Affiliations
History
  • Received：2024-07-20
Funding
Affiliations
    1.School of Traditional Chinese and Western Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
    2.Department of Cardiology, Affiliated Hospital of Gansu University of Chinese Medicine, Lanzhou 730030, Gansu Province, China
References
Share
https://castjournals.cast.org.cn/joweb/zglcylxzz/EN/10.13699/j.cnki.1001-6821.2025.02.025
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62662699(Operation and Technical Support)
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House