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Research status on traditional Chinese medicine regulating cell apoptosis for the treatment of non-small cell lung cancer
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Si-qi KONG1a, Juan CHUAN1a, Jin-tian LI1a, 1b, Jian-qing LIANG1a, Yi ZHANG1a
Chinese Journal of Clinical Pharmacology | 2025, 41(1) : 100 - 104
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Chinese Journal of Clinical Pharmacology | 2025, 41(1): 100-104
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Research status on traditional Chinese medicine regulating cell apoptosis for the treatment of non-small cell lung cancer
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Si-qi KONG1a, Juan CHUAN1a, Jin-tian LI1a, 1b, Jian-qing LIANG1a, Yi ZHANG1a
Affiliations
  • 1a.The Clinical College of Traditional Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
  • 1b.The Key Laboratory of The Ministry of Education of Dunhuang Medicine and Transformation, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
Published: 2025-01-17 doi: 10.13699/j.cnki.1001-6821.2025.01.021
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Non-small cell lung cancer (NSCLC) constitutes the largest portion of lung cancer overall, with high incidence and mortality rates. Apoptosis, is a hot focus in the clinical treatment of NSCLC, its main pathways include the extrinsic death receptor pathway, intrinsic mitochondrial apoptosis pathway and endoplasmic reticulum stress pathway, collectively regulating the cellular apoptosis process. Traditional Chinese medicine (TCM) has significant efficacy in the treatment and prognosis of NSCLC, with advantages such as boosting the body’s resistance and less adverse drug reactions. Studies have shown that various individual Chinese herbal medicines and compound formulas can treat NSCLC through the apoptosis pathway, alleviating the adverse drug reaction of radiotherapy and chemotherapy. Based on this, this article summarizes recent domestic and international literature, focusing on apoptosis, to summarize the research progress of TCM in treating NSCLC by regulating apoptosis, aiming to provide reference for clinical treatment for NSCLC.

traditional Chinese medicine  /  non-small cell lung cancer  /  apoptosis  /  death receptor pathway  /  mitochondrial apoptosis pathway  /  endoplasmic reticulum stress pathway
Si-qi KONG, Juan CHUAN, Jin-tian LI, Jian-qing LIANG, Yi ZHANG. Research status on traditional Chinese medicine regulating cell apoptosis for the treatment of non-small cell lung cancer[J]. Chinese Journal of Clinical Pharmacology, 2025 , 41 (1) : 100 -104 . DOI: 10.13699/j.cnki.1001-6821.2025.01.021
Year 2025 volume 41 Issue 1
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doi: 10.13699/j.cnki.1001-6821.2025.01.021
  • Receive Date:2024-05-29
  • Online Date:2026-08-04
  • Published:2025-01-17
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  • Received:2024-05-29
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    1a.The Clinical College of Traditional Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
    1b.The Key Laboratory of The Ministry of Education of Dunhuang Medicine and Transformation, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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