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Analysis of the rationality of internet outpatient prescription in children’s specialized hospitals based on the rational drug use system
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Zhao-yang DU, Qiang SHI, Zi-yang SONG, Xin-wei CHEN, Jin-jing MA, Xin LIU, Lei ZHANG, Jing-hai WEI, Peng GUO
Chinese Journal of Clinical Pharmacology | 2025, 41(24) : 3536 - 3542
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Chinese Journal of Clinical Pharmacology | 2025, 41(24): 3536-3542
Rational Use of Drugs
Analysis of the rationality of internet outpatient prescription in children’s specialized hospitals based on the rational drug use system
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Zhao-yang DU, Qiang SHI, Zi-yang SONG, Xin-wei CHEN, Jin-jing MA, Xin LIU, Lei ZHANG, Jing-hai WEI, Peng GUO
Affiliations
  • Department of Pharmacy, Beijing Children′s Hospital, Capital Medical University, National Center for Children′s Health, Beijing 100045, China
Published: 2025-12-28 doi: 10.13699/j.cnki.1001-6821.2025.24.014
Outline
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Objective

In the context of "internet plus health care", the annual internet outpatient prescriptions of a tertiary children′s hospital (Beijing Children′s Hospital affiliated to Capital Medical University, hereinafter referred to as the hospital) were taken as the objects, and the rationality of prescriptions was analyzed based on the rational drug use system, and the types, causes and drug characteristics of unreasonable treatments were identified to provide data support for the rational drug use management of pediatric Internet outpatient.

Methods

All prescriptions from the hospital′s internet outpatient hospital information system (HIS) in 2024 were collected and summarized. Review results were obtained by relying on the Puhua Hecheng Rational Drug Use System, and true positive irrational prescriptions were determined by combining with pharmacists′ manual re-evaluation. Statistical analysis was performed using Excel software.

Results

A total of 58 560 internet outpatient prescriptions were included. The rational drug use software reviewed 1 334 machine-screened positive irrational prescriptions, and 438 true-positive irrational prescriptions were confirmed after manual re-evaluation, with an overall irrational rate of 0.75%. Among the 438 prescriptions, 93.61% involved only one irrational drug item, and a total of 559 medication problems were detected. Among these, inappropriate indication accounted for the highest proportion (63.51%), which was identified as the primary factor by Pareto analysis. Among the problems of inappropriate dosage and usage, 80.22% involved two combined issues (primarily single-dose overdose and daily-dose overdose, accounting for 61.54%). Inappropriate administration route was mainly attributed to non-standard labeling of "as needed" (70.00%), primarily involving nebulized drugs and nutritional supplements. The top three medications involved in irrational prescriptions were all nutritional supplements and vitamins, with this category ranking first among medication classifications.

Conclusion

The overall rationality of prescriptions in the hospital's pediatric internet-based outpatient service is relatively high. However, inappropriate indications and non-standard dosage and usage remain core issues. Targeted optimization of rational drug use system rules, enhanced pharmaceutical intervention, strengthened physician training, and improved remote consultation processes are needed to enhance medication safety and achieve continuous improvement.

rational drug use  /  Internet outpatient service  /  prescription review  /  children
Zhao-yang DU, Qiang SHI, Zi-yang SONG, Xin-wei CHEN, Jin-jing MA, Xin LIU, Lei ZHANG, Jing-hai WEI, Peng GUO. Analysis of the rationality of internet outpatient prescription in children’s specialized hospitals based on the rational drug use system[J]. Chinese Journal of Clinical Pharmacology, 2025 , 41 (24) : 3536 -3542 . DOI: 10.13699/j.cnki.1001-6821.2025.24.014
Year 2025 volume 41 Issue 24
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doi: 10.13699/j.cnki.1001-6821.2025.24.014
  • Receive Date:2025-11-24
  • Online Date:2026-08-05
  • Published:2025-12-28
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  • Received:2025-11-24
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    Department of Pharmacy, Beijing Children′s Hospital, Capital Medical University, National Center for Children′s Health, Beijing 100045, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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