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Research progress of traditional Chinese medicine regulating ferroptosis in the treatment of sepsis-induced cardiomyopathy
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Ya-yun WANG, Tian-peng HE, Long-fei GUO
Chinese Journal of Clinical Pharmacology | 2025, 41(22) : 3248 - 3254
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Chinese Journal of Clinical Pharmacology | 2025, 41(22): 3248-3254
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Research progress of traditional Chinese medicine regulating ferroptosis in the treatment of sepsis-induced cardiomyopathy
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Ya-yun WANG, Tian-peng HE, Long-fei GUO
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  • Department of Critical Care Medicine, Gansu Provincial People’s Hospital, Lanzhou 730000, Gansu Province, China
Published: 2025-11-28 doi: 10.13699/j.cnki.1001-6821.2025.22.015
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Sepsis-induced cardiomyopathy is a common cardiovascular complication among septic patients, which significantly increases mortality rates. Ferroptosis is an iron-dependent form of regulated cell death characterized by increased lipid reactive oxygen species (ROS), which causes lipid peroxidation and cell membrane damage. Increasing evidence has highlighted a significant link between ferroptosis and sepsis-induced cardiomyopathy, in which traditional Chinese medicine (TCM) exhibits promising therapeutic potential. This article reviews the mechanism of ferroptosis and current advances in the use of TCM active ingredients and formulated preparations to target ferroptosis in treating sepsis-induced cardiomyopathy, aiming to offer new perspectives for clinical management.

traditional Chinese medicine  /  ferroptosis  /  sepsis-induced cardiomyopathy  /  sepsis
Ya-yun WANG, Tian-peng HE, Long-fei GUO. Research progress of traditional Chinese medicine regulating ferroptosis in the treatment of sepsis-induced cardiomyopathy[J]. Chinese Journal of Clinical Pharmacology, 2025 , 41 (22) : 3248 -3254 . DOI: 10.13699/j.cnki.1001-6821.2025.22.015
Year 2025 volume 41 Issue 22
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doi: 10.13699/j.cnki.1001-6821.2025.22.015
  • Receive Date:2025-08-05
  • Online Date:2026-08-05
  • Published:2025-11-28
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  • Received:2025-08-05
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    Department of Critical Care Medicine, Gansu Provincial People’s Hospital, Lanzhou 730000, Gansu Province, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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