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As a crucial type of non-coding ribonucleic acid (RNA), microRNA (miRNA) is widely involved in various biological processes such as cell proliferation, differentiation, and apoptosis. In recent years, increasing attention has been paid to the regulatory role of miRNAs in vascular endothelial cells, particularly their potential impact on the pathological state of venous thrombosis. Studies have shown that miRNAs may play a key role in the occurrence and development of venous thrombosis by regulating the functions of vascular endothelial cells. However, the specific mechanisms underlying the role of miRNAs in this process remain incompletely understood, and clinical applications face numerous challenges. This review aims to summarize the regulatory mechanisms of miRNAs in vascular endothelial cells and research progress in venous thrombosis, explore their prospects as potential therapeutic targets, and outline current research challenges and future directions, thereby providing new insights into the role of miRNAs in venous thrombosis.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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