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Ciprofol is a type of innovative drug independently developed in China and with global independent intellectual property rights. It is a short-acting intravenous sedative based on the structural modification of propofol. It has the advantages of fast onset, fast recovery, high titer, good selectivity, low accumulation, stable respiratory circulation, and few adverse reactions, providing a better choice for clinical stable sedation and anesthesia, and has good clinical application potential. A series of clinical studies have evaluated the sedative effects of ciprofol in various procedures and settings, demonstrating its application in endoscopic sedation, general anesthesia, and sedation during intensive care. This paper reviewed the mechanism of action, pharmacokinetics and pharmacokinetic properties of ciprofol, and the progress of clinical application research, and evaluated the effectiveness and safety of ciprofol by synthesizing relevant clinical trial data.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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