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Research status of traditional Chinese medicine regulating PI3K/Akt signaling pathway to intervene in endometriosis
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Ya-ru LI1, Hong QU2, Ya-nan ZHANG1, Cai-feng XU2
Chinese Journal of Clinical Pharmacology | 2025, 41(4) : 586 - 590
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Chinese Journal of Clinical Pharmacology | 2025, 41(4): 586-590
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Research status of traditional Chinese medicine regulating PI3K/Akt signaling pathway to intervene in endometriosis
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Ya-ru LI1, Hong QU2, Ya-nan ZHANG1, Cai-feng XU2
Affiliations
  • 1.Clinical College of Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
  • 2.Department of Gynecology and Obstetrics, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, Gansu Province, China
Published: 2025-02-28 doi: 10.13699/j.cnki.1001-6821.2025.04.028
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The phosphatidy linositol 3-kinase/protein kinase B (PI3K/Akt) signaling pathway promotes the occurrence and development of endometriosis (EMs) by participating in angiogenesis and cell invasion. In recent years, with the deepening of pharmacological research, traditional Chinese medicine (TCM) has been widely recognized for its advantages of multi-targets, multi-pathways, and fewer adverse drug reactions, and the research on the treatment of EMs by TCM through the modulation of the PI3K/Akt signaling pathway has also achieved certain results. Based on this, this paper analyzes the roles of single Chinese medicine, Chinese medicinal compound and TCM therapeutic methods in regulating the PI3K/Akt signaling pathway in the treatment of EMs, with the aim of providing a theoretical basis for the treatment of EMs by TCM.

traditional Chinese medicine  /  endometriosis  /  phosphatidylinositol-3 kinase/protein kinase B signaling pathway  /  research progress
Ya-ru LI, Hong QU, Ya-nan ZHANG, Cai-feng XU. Research status of traditional Chinese medicine regulating PI3K/Akt signaling pathway to intervene in endometriosis[J]. Chinese Journal of Clinical Pharmacology, 2025 , 41 (4) : 586 -590 . DOI: 10.13699/j.cnki.1001-6821.2025.04.028
Year 2025 volume 41 Issue 4
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doi: 10.13699/j.cnki.1001-6821.2025.04.028
  • Receive Date:2024-06-24
  • Online Date:2026-08-04
  • Published:2025-02-28
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  • Received:2024-06-24
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Affiliations
    1.Clinical College of Chinese Medicine, Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
    2.Department of Gynecology and Obstetrics, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, Gansu Province, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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