To analyze the application and funded projects in the field of clinical pharmacology supported by the National Natural Science Foundation of China (NSFC) from 2015 to 2024, aiming to provide a reference for the application.

Information on the application and funded projects under the "Clinical Pharmacology (H3511)" code from 2015 to 2024 was collected from the NSFC management information system, including funding year, project name, project category, funding amount, keywords, research directions, etc. A database was established based on this information for statistical analysis.

From 2015 to 2024, 2 031 applications were received for general, young scientist, and regional scientist foundation in the clinical pharmacology research field, with 320 projects funded, accumulating a direct funding of 118.48 million yuan. The number and amount of funded projects showed a fluctuating upward trend. The diseases studied in the applications were mainly concentrated in malignant tumors, cardiovascular and cerebrovascular diseases, neuropsychiatric diseases, and metabolic diseases. The research directions of the applications and funded projects were mainly focused on personalized medication, drug adverse reactions and toxicity, and clinical biomarkers, accounting for 67.6% and 70.3% of the total number of application and funded projects, respectively.

With the emergence of new methods and technologies, clinical pharmacology has developed rapidly, and basic research in this field has increasingly attracted attention. The NSFC has always emphasized support for this field. However, there are still some issues of the applications, such as the need to strengthen clinical characteristics, uneven distribution of disease types and research directions, and unbalanced development within the discipline, which require increased attention from clinical pharmacology researchers.