In this study, a catalyst with bimetallic CuCo-MOF-74 dispersed on semi-coke (SC) (CuCo-MOF-74_x/SC) was successfully prepared by one-pot hydrothermal synthesis, and the degradation behavior and mechanism for aqueous bisphenol A (BPA) via persulfate (PMS) activation was systemically studied. The characterization results showed that CuCo-MOF-74 was uniformly dispersed onto the surface of semi-coke activated carbon, and the specific surface area of CuCo-MOF-74₂/SC was 582.04m²/g. For BPA degradation, under the optimum conditions (0.2g/L PMS, 0.1g/L catalyst), the CuCo-MOF-74₂/SC/PMS system achieved a degradation efficiency of 95.01% for 20mg/L BPA in 30min and the mineralization rate of 54.7%, which was significantly higher than that of the CuCo-MOF-74/PMS system, and the reaction rate constant of CuCo-MOF-74₂/SC (0.1113min^-1) was 3.4 times of CuCo-MOF-74 (0.0324min^-1). After 5 cycles, the degradation efficiency of CuCo-MOF-74₂/SC decreased from 94.83% to 72.56%, which was remarkably higher than that of CuCo-MOF-74 (from 76.95% to 21.49%). In the CuCo-MOF-74₂/SC/PMS system, both free radicals (·OH, and ) and non-radicals (¹O₂ and electron transfer) were involved in the degradation of BPA, and free radicals oxidation played a major role. The loading of CuCo-MOF-74 on SC significantly enhances the stability and improves specific surface area of CuCo-MOF-74, thereby elevating the degradation efficiency for BPA in water. This study provides the important guiding significance for the development of MOF-based catalysts.