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Methane production potential and material flow for anaerobic digestion of typical antibiotic fermentation residues
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Jian-jun REN1, Li-xia ZHU1, 2, Dong-min YIN1, *, Hong-gang MAO1, 2, Tao-li HUHE1, Dong-ze NIU1, Chun-yu LI1, Rui TANG1, Xi-long XIA1
China Environmental Science | 2025, 45(3) : 1375 - 1384
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China Environmental Science | 2025, 45(3): 1375-1384
Solid Waste
Methane production potential and material flow for anaerobic digestion of typical antibiotic fermentation residues
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Jian-jun REN1, Li-xia ZHU1, 2, Dong-min YIN1, *, Hong-gang MAO1, 2, Tao-li HUHE1, Dong-ze NIU1, Chun-yu LI1, Rui TANG1, Xi-long XIA1
Affiliations
  • 1.Changzhou Key Laboratory of Biomass Green, Safe & High Value Utilization, Institute of Urban and Rural Mining, Changzhou University, Changzhou 213164, China
  • 2.School of Pharmacy & School of Biological and Food Engineering, Changzhou University, Changzhou 213164, China
Published: 2025-03-20
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To investigate the feasibility of anaerobic digestion of antibiotic fermentation residues(AFR)as sole substrates, several typical AFR, including erythromycin fermentation residue(EFR), cephalosporin fermentation residue(CFR), and penicillin fermentation residue(PFR)were chosen as raw materials for digestion in this study. Batch assays of methane production potential and kinetics experiments were conducted at mesophilic temperature(35±1℃)to explore the basic characteristics of anaerobic digestion of different AFR. Mass balance and correlations between basic characteristics of raw materials and digestion performance were compared and contrasted. Results showed that EFR had the highest methane production potential, approximately 226mL/g VS, which was 27.0% and 20.2% higher than CFR and PFR, respectively. Distinct kinetic characteristics and metabolic activity differences were exhibited by different antibiotic fermentation residues during anaerobic fermentation. The highest biogas production rate, which was 13.2mL/(g VS·d), was found in PFR. A clear two-stage characteristic was exhibited by EFR, with the first-order kinetic constants K1 and K2 being 0.0336 and 0.2012d-1, respectively. Material balance verification confirmed the reliability of the experimental results, and the remaining insoluble substances significantly impact the startup and stability of the anaerobic system. Correlation analysis indicated that the parameters of SCOD/TCOD, C/N, protein, and fat content in the fermentation residues are important for assessing their performance in anaerobic fermentation, suggesting that optimizing the characteristics of the fermentation residues can improve fermentation efficiency. It was demonstrated that antibiotic fermentation residues treated with antibiotic removal can serve as a single substrate for anaerobic fermentation, providing a new solution for the resource utilization of fermentation residues.

antibiotic fermentation residues  /  anaerobic digestion  /  biogas production dynamics  /  mass balance  /  correlation analysis
Jian-jun REN, Li-xia ZHU, Dong-min YIN, Hong-gang MAO, Tao-li HUHE, Dong-ze NIU, Chun-yu LI, Rui TANG, Xi-long XIA. Methane production potential and material flow for anaerobic digestion of typical antibiotic fermentation residues[J]. China Environmental Science, 2025 , 45 (3) : 1375 -1384 .
Year 2025 volume 45 Issue 3
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  • Receive Date:2024-08-20
  • Online Date:2026-03-18
  • Published:2025-03-20
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  • Received:2024-08-20
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Affiliations
    1.Changzhou Key Laboratory of Biomass Green, Safe & High Value Utilization, Institute of Urban and Rural Mining, Changzhou University, Changzhou 213164, China
    2.School of Pharmacy & School of Biological and Food Engineering, Changzhou University, Changzhou 213164, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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