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The correlation between early or late natural menopausal age and muscle mass percentage and bone mass percentage in postmenopausal women
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Jiaoling LUO1, Weisen ZHANG2, Zhihao CHAI1, Feng ZHU2, Tong ZHU2, Yali JIN2, Jing PAN2, Chaoqiang JIANG2
Chinese Journal of Public Health | 2025, 41(1) : 55 - 60
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Chinese Journal of Public Health | 2025, 41(1): 55-60
• Survey and Report •
The correlation between early or late natural menopausal age and muscle mass percentage and bone mass percentage in postmenopausal women
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Jiaoling LUO1, Weisen ZHANG2, Zhihao CHAI1, Feng ZHU2, Tong ZHU2, Yali JIN2, Jing PAN2, Chaoqiang JIANG2
Affiliations
  • 1Laboratory of Molecular Epidemiology, Twelfth People's Hospital Affiliated to Guangzhou Medical University, Guangzhou 510620, China
  • 2Guangzhou Biobank Cohort Research Group, Guangzhou Twelfth People’s Hospital, Guangzhou 510620, China
Published: 2025-01-10 doi: 10.11847/zgggws1145410
Outline
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Objective

To analyze the correlation between early or late natural menopausal age and muscle mass percentage and bone mass percentage in postmenopausal women, and to provide a reference for health care of postmenopausal women.

Methods

A total of 2 059 naturally menopausal women were selected from the Guangzhou Chronic Disease Prospective Cohort Study of Middle-aged and Elderly People. Baseline survey data were collected from November 2017 to January 2020, including general demographic characteristics, female physiological data, and body composition indicators such as muscle mass percentage and bone mass. Generalized linear models were used for data analysis.

Results

The average age and average menopausal age of the participants were (59.1±5.1) years and (50.4±2.9) years, respectively. After adjusting for relevant confounding factors, compared with the normal menopausal age group, both the early menopausal age group (β=–1.02, 95%CI: –1.83 to –0.21) and the late menopausal age group (β=–0.75, 95% CI: –1.43 to –0.06) were associated with decreased muscle mass percentage (both P values <0.05). No association was found between early or late menopausal age and bone mass percentage.

Conclusions

Early or late natural menopause is associated with decreased muscle mass percentage in postmenopausal women, but not with bone mass percentage.

menopausal age  /  muscle ratio  /  bone mass percentage  /  middle-aged and elderly women
罗娇玲, 张维森, 柴智浩, 朱峰, 朱彤, 靳雅丽, 潘静, 江朝强. 绝经年龄与绝经后肌肉率和骨量占比关系. 中国公共卫生, 2025 , 41 (1) : 55 -60 . DOI: 10.11847/zgggws1145410
Jiaoling LUO, Weisen ZHANG, Zhihao CHAI, Feng ZHU, Tong ZHU, Yali JIN, Jing PAN, Chaoqiang JIANG. The correlation between early or late natural menopausal age and muscle mass percentage and bone mass percentage in postmenopausal women[J]. Chinese Journal of Public Health, 2025 , 41 (1) : 55 -60 . DOI: 10.11847/zgggws1145410
Year 2025 volume 41 Issue 1
72
29
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Article Info
doi: 10.11847/zgggws1145410
  • Receive Date:2024-09-02
  • Online Date:2026-10-25
  • Published:2025-01-10
Article Data
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History
  • Received:2024-09-02
  • Revised:2024-10-09
  • Accepted:2024-11-19
Affiliations
    1Laboratory of Molecular Epidemiology, Twelfth People's Hospital Affiliated to Guangzhou Medical University, Guangzhou 510620, China
    2Guangzhou Biobank Cohort Research Group, Guangzhou Twelfth People’s Hospital, Guangzhou 510620, China

Corresponding:

ZHANG Weisen, E-mail:
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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