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Hepatitis C epidemic characteristics in Shanghai, 2020–2023: a surveillance data analysis
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Kaiyun CHEN1, Zuping GUO2, Di XU1, Wei WANG3, Xin SHEN1, Hong REN1
Chinese Journal of Public Health | 2025, 41(9) : 1069 - 1073
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Chinese Journal of Public Health | 2025, 41(9): 1069-1073
• Special Report — United in the Fight Against Hepatitis C •
Hepatitis C epidemic characteristics in Shanghai, 2020–2023: a surveillance data analysis
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Kaiyun CHEN1, Zuping GUO2, Di XU1, Wei WANG3, Xin SHEN1, Hong REN1
Affiliations
  • 1Institute for Tuberculosis and AIDS Control & Prevention, Shanghai Municipal Center for Disease Control & Prevention, Shanghai 200336, China
  • 2Hongkou District Center for Disease Control & Prevention (Hongkou District Health Supervision Institute), Shanghai 200082, China
  • 3Pathogen Detection Institute, Shanghai Municipal Center for Disease Control & Prevention, Shanghai 200336, China
Published: 2025-09-10 doi: 10.11847/zgggws1147013
Outline
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Objective

To systematically analyze the integrated surveillance data of hepatitis C (HC) in Shanghai and provide a scientific basis for the elimination of HC.

Methods

The reported HC cases, hepatitis C virus (HCV) genotypes, and sentinel surveillance data were collected based on the integrated HC surveillance work in Shanghai from 2020 to 2023. The incidence trend, distribution, HCV genotypes, and high-risk/key populations of HC in Shanghai were analyzed.

Results

The reported incidences of acute and chronic HC in Shanghai from 2020 to 2023 were 0.04/100 000 and 6.93/100 000, respectively. The reported chronic cases were mainly males, middle-aged and elderly people, and downtown residents. Genotypes 1b (40.36%), 3b (14.80%), 3a (11.43%), 6a (10.09%), and 6n (6.05%) were the principal subtypes of HCV. The HCV antibody-positive rate in drug users, family members of HC patients, and people who died of liver disease were 31.88%, 10.00%, and 6.00%, respectively, which were significantly higher than that in other high-risk/key populations. The departments of hepatology (4.79%), traditional Chinese medicine/acupuncture and moxibustion (2.53%), general outpatient (1.85%), hemodialysis (1.58%), and infectious diseases (1.41%) were the key departments of medical institutions with higher HCV-antibody positive rates.

Conclusions

HC was low-epidemic in Shanghai from 2020 to 2023, with higher infection rates observed among drug users and family members of HC patients. Optimization of the integrated surveillance system for HC is of great value for understanding the epidemiological characteristics, infection status of high-risk/key populations, rational allocation of medical and health resources, and promoting the elimination of HC.

hepatitis C  /  high-risk/key populations  /  genotypes  /  epidemic characteristics  /  Shanghai
陈恺韵, 郭足平, 徐迪, 王葳, 沈鑫, 任宏. 2020—2023年上海市丙型肝炎流行特征分析. 中国公共卫生, 2025 , 41 (9) : 1069 -1073 . DOI: 10.11847/zgggws1147013
Kaiyun CHEN, Zuping GUO, Di XU, Wei WANG, Xin SHEN, Hong REN. Hepatitis C epidemic characteristics in Shanghai, 2020–2023: a surveillance data analysis[J]. Chinese Journal of Public Health, 2025 , 41 (9) : 1069 -1073 . DOI: 10.11847/zgggws1147013
Year 2025 volume 41 Issue 9
69
28
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Article Info
doi: 10.11847/zgggws1147013
  • Receive Date:2025-01-26
  • Online Date:2026-10-25
  • Published:2025-09-10
Article Data
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History
  • Received:2025-01-26
  • Revised:2025-07-13
  • Accepted:2025-08-01
Affiliations
    1Institute for Tuberculosis and AIDS Control & Prevention, Shanghai Municipal Center for Disease Control & Prevention, Shanghai 200336, China
    2Hongkou District Center for Disease Control & Prevention (Hongkou District Health Supervision Institute), Shanghai 200082, China
    3Pathogen Detection Institute, Shanghai Municipal Center for Disease Control & Prevention, Shanghai 200336, China

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REN Hong, E-mail:
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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