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Definition, methods, and applications of causal machine learning in medicine
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Ben NIU1, Mengjie WAN1, Jue LIU2
Chinese Journal of Public Health | 2025, 41(7) : 769 - 775
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Chinese Journal of Public Health | 2025, 41(7): 769-775
• Perspective •
Definition, methods, and applications of causal machine learning in medicine
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Ben NIU1, Mengjie WAN1, Jue LIU2
Affiliations
  • 1School of Management, Hospital Management Research Institute, Shenzhen University, Shenzhen 518060, China
  • 2School of Public Health, Peking University; Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing 100191, China
Published: 2025-07-10 doi: 10.11847/zgggws1146966
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With therapid advancement of medical science and technology, machine learning has become an integral component of precision medicine. However, traditional machine learning methods often focus on the correlation analysis between independent and outcome variables, which can hinder their ability to accurately identify causal relationships. This limitation leads to biased clinical conclusions, impacting the precision and reliability of clinical decision-making. Causal machine learning has emerged as a promising approach to overcome these limitations, and its application in the medical field is expanding. This paper systematically explores the definition and core concepts of causal machine learning, clarifies its specific application scope in disease prevention, and delves into its unique advantages over traditional machine learning, statistical models, and causal inference. Furthermore, it outlines the practical methodologies, operational steps, and key technical aspects of causal machine learning in medical practice. By presenting specific case studies, the paper discusses the applications of causal machine learning in disease prevention, highlighting both its strengths and weaknesses. Ultimately, the goal is to standardize and promote the scientific application of causal machine learning in the medical domain.

causal machine learning  /  disease prevention  /  causal inference
牛奔, 万梦洁, 刘珏. 因果机器学习的原理、方法及其在疾病防治的创新应用. 中国公共卫生, 2025 , 41 (7) : 769 -775 . DOI: 10.11847/zgggws1146966
Ben NIU, Mengjie WAN, Jue LIU. Definition, methods, and applications of causal machine learning in medicine[J]. Chinese Journal of Public Health, 2025 , 41 (7) : 769 -775 . DOI: 10.11847/zgggws1146966
Year 2025 volume 41 Issue 7
100
45
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Article Info
doi: 10.11847/zgggws1146966
  • Receive Date:2025-01-20
  • Online Date:2026-10-25
  • Published:2025-07-10
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History
  • Received:2025-01-20
  • Revised:2025-04-10
  • Accepted:2025-05-30
Affiliations
    1School of Management, Hospital Management Research Institute, Shenzhen University, Shenzhen 518060, China
    2School of Public Health, Peking University; Key Laboratory of Epidemiology of Major Diseases (Peking University), Ministry of Education, Beijing 100191, China

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表12种不同金属材料的力学参数
科
Family
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Number of
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Number of
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Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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