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Current situation, challenges, and future prospects of hepatitis B vaccination in China: a review
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Chengbin SHI1, 2, Jiaxin XIE1, 2, Jiamin QIU1, 2, Xiaoping SHAO3, Fangfang ZENG1, 2, Xiaofeng LIANG1, 2, 3
Chinese Journal of Public Health | 2026, 42(4) : 464 - 469
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Chinese Journal of Public Health | 2026, 42(4): 464-469
• Review •
Current situation, challenges, and future prospects of hepatitis B vaccination in China: a review
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Chengbin SHI1, 2, Jiaxin XIE1, 2, Jiamin QIU1, 2, Xiaoping SHAO3, Fangfang ZENG1, 2, Xiaofeng LIANG1, 2, 3
Affiliations
  • 1Department of Preventive Medicine, School of Medicine, Jinan University/Disease Control and Prevention Institute of Jinan University/Kangtai Biological Vaccine Industry Research Institute, Jinan University, Guangzhou 510632, China
  • 2Key Laboratory of Viral Pathogenesis and Infection Prevention and Control, Ministry of Education, Jinan University, Guangzhou 510632, China
  • 3Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China
Published: 2026-04-10 doi: 10.11847/zgggws1148602
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It is about to enter the decisive five years of the 2030 goal set by the World Health Organization to eliminate hepatitis. As one of the countries with the heaviest burden of hepatitis B virus, China faces self-evident challenges. Hepatitis B vaccination has been scientifically verified as the most powerful weapon to eliminate hepatitis B at present. Since 1992, the hepatitis B vaccination strategy has been implemented and continuously improved in China, achieving remarkable success. Accordingly, significant progress has been made in the prevention and control of hepatitis B in China. However, up to now, China still faces multiple problems to be solved in hepatitis B vaccination, and it is particularly urgent to further improve the hepatitis B vaccination strategy. This review aims to provide a useful reference for the continuous optimization of hepatitis B vaccination strategies in China by reviewing the evolution of hepatitis B vaccination strategies in China, delving into the current status of vaccination, analyzing the main challenges that still exist, and making an outlook on the future development of hepatitis B vaccination strategies.

hepatitis B  /  vaccine  /  vaccination strategy  /  analysis of current status  /  China
石程宾, 谢佳欣, 邱嘉敏, 邵晓萍, 曾芳芳, 梁晓峰. 中国乙肝疫苗接种现状、挑战与未来展望. 中国公共卫生, 2026 , 42 (4) : 464 -469 . DOI: 10.11847/zgggws1148602
Chengbin SHI, Jiaxin XIE, Jiamin QIU, Xiaoping SHAO, Fangfang ZENG, Xiaofeng LIANG. Current situation, challenges, and future prospects of hepatitis B vaccination in China: a review[J]. Chinese Journal of Public Health, 2026 , 42 (4) : 464 -469 . DOI: 10.11847/zgggws1148602
Appendix
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Year 2026 volume 42 Issue 4
113
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Article Info
doi: 10.11847/zgggws1148602
  • Receive Date：2025-08-06
  • Online Date：2026-10-23
  • Published：2026-04-10
Article Data
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History
  • Received：2025-08-06
  • Revised：2025-09-26
  • Accepted：2025-11-10
Affiliations
    1Department of Preventive Medicine, School of Medicine, Jinan University/Disease Control and Prevention Institute of Jinan University/Kangtai Biological Vaccine Industry Research Institute, Jinan University, Guangzhou 510632, China
    2Key Laboratory of Viral Pathogenesis and Infection Prevention and Control, Ministry of Education, Jinan University, Guangzhou 510632, China
    3Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China

Corresponding:

LIANG Xiaofeng, E-mail:
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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