Full
Outline
To strengthen the biosafety management of pathogen microbiology laboratories, understand the current management status of biosafety laboratories in various institutions, analyze existing issues, and explore solutions.
Using the registration system, we obtained the registration data of pathogen microbiology laboratories in Hangzhou as of the end of May 2023. From June to September 2023, we randomly selected 221 entities responsible for establishing pathogen microbiology laboratories in Hangzhou and their 636 successfully registered subordinate laboratories. On-site evaluation of pathogen microbiology laboratories in Hangzhou was conducted in accordance with the Specification for the Evaluation of Biosafety Laboratory Management and the on-site evaluation results regarding laboratory infection risks were analyzed.
The overall compliance rate with biosafety requirements among the inspected institutions in Hangzhou was 95.22%. There were differences in overall compliance rate among various types of institutions (χ2 = 431.816, P < 0.001). The laboratories from different institutions showed differences in compliance rates (P < 0.05) in organizational management, laboratory facilities/equipment, personnel management, management of strains/samples, management of laboratory waste, housekeeping management, and fire safety management. No difference was observed in the compliance rates for routine management evaluation indicators (P > 0.05).
The laboratories in medical institutions of the county level and above and independent testing institutions in Hangzhou demonstrate good biosafety management status, whereas the management status of laboratories in private medical institutions, biotechnology enterprises, and township health centers needs improvement.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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