Full
Outline
To explore the association between erectile dysfunction (ED) and risk of coronary heart disease (CHD), thus providing a theoretical basis for identifying the potential clinical value of ED in CHD risk prediction.
The English-language cohort studies on the association between ED and CHD published worldwide were systematically retrieved from PubMed, Web of Science, Scopus, and Embase, supplemented by reference tracing, with the time interval from database inception to September 11, 2025. A meta-analysis of the included studies was performed in Stata 18.0.
Finally, 7 cohort studies involving 14 397 participants with 1 395 incident cases of CHD were included. Meta-analysis showed that individuals with ED had a CHD risk 1.41 fold (RR=1.41, 95%CI: 1.28–1.56) of that among those without ED. Subgroup analyses revealed that ED was associated with an increased risk of CHD across subgroups stratified by age (≤70 years vs. >70 years), follow-up duration (≤5 years vs. >5 years), and ED diagnostic criteria (5-item International Index of Erectile Function [IIEF-5] vs. self-reported ED), with all P-values < 0.05. Sensitivity analyses and tests for publication bias indicated no significant publication bias among the included studies, and the overall results were robust and stable.
ED may be associated with an elevated risk of CHD.
71
26
| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
关闭全屏
No. 86 Xueyuan South Road, Haidian District, Beijing
010-62662699(Operation and Technical Support)
qkjq@cast.org.cn
Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House
