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Mechanisms of trace element selenium in the prevention and treatment of diseases caused by viral infections: a review
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Yuhui ZENG, Jiali LI, Tianyu ZHOU, Bing ZHU, Yinghua LI
Chinese Journal of Public Health | 2026, 42(9) : 1148 - 1152
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Chinese Journal of Public Health | 2026, 42(9): 1148-1152
• Review •
Mechanisms of trace element selenium in the prevention and treatment of diseases caused by viral infections: a review
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Yuhui ZENG, Jiali LI, Tianyu ZHOU, Bing ZHU, Yinghua LI
Affiliations
  • Center Laboratory, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou 510120, China
Published: 2026-09-10 doi: 10.11847/zgggws1149089
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Infectious diseases have been spreading rapidly across the globe, posing serious impacts on human health and the global economy. At present, the long-term use of antiviral drugs is accompanied by issues such as drug resistance and adverse reactions. Therefore, developing novel antiviral agents is particularly important. Selenium is an essential trace element for humans and animals. Individuals or animals with low selenium levels are more susceptible to viruses, which can lead to more severe illnesses. In the prevention and treatment of viral infections, selenium exerts antioxidant activity, regulates the immune system, protects the stability of endothelial cells, and participates in the regulation of signaling pathways. The correlation between selenium and infectious diseases has attracted considerable attention. This article reviews the antiviral mechanisms of selenium, new antiviral targets of selenium, and the current methods of selenium supplementation, aiming to provide new ideas and medication approaches for the prevention and treatment of viral diseases.

viral infection  /  infectious diseases  /  trace element  /  selenium  /  antioxidant activity  /  immunity
曾毓慧, 李佳丽, 周天雨, 朱冰, 李英华. 微量元素硒防治病毒感染作用机制研究进展. 中国公共卫生, 2026 , 42 (9) : 1148 -1152 . DOI: 10.11847/zgggws1149089
Yuhui ZENG, Jiali LI, Tianyu ZHOU, Bing ZHU, Yinghua LI. Mechanisms of trace element selenium in the prevention and treatment of diseases caused by viral infections: a review[J]. Chinese Journal of Public Health, 2026 , 42 (9) : 1148 -1152 . DOI: 10.11847/zgggws1149089
Year 2026 volume 42 Issue 9
97
45
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doi: 10.11847/zgggws1149089
  • Receive Date:2025-10-15
  • Online Date:2026-10-23
  • Published:2026-09-10
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  • Received:2025-10-15
  • Revised:2026-01-10
  • Accepted:2026-04-04
Affiliations
    Center Laboratory, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou 510120, China

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LI Yinghua, E-mail:
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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