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Application of large language models in predicting trends of notifiable infectious diseases in Guangzhou: based on 2024 surveillance data
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Yuqian WU, Shuwen DONG, Xinrong XIANG, Zongxin LI, Jianzhe GAN, Pengzhe QIN
Chinese Journal of Public Health | 2026, 42(5) : 551 - 555
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Chinese Journal of Public Health | 2026, 42(5): 551-555
• Special Report—Applications of Artificial Intelligence in Public Health •
Application of large language models in predicting trends of notifiable infectious diseases in Guangzhou: based on 2024 surveillance data
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Yuqian WU, Shuwen DONG, Xinrong XIANG, Zongxin LI, Jianzhe GAN, Pengzhe QIN
Affiliations
  • Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China
Published: 2026-05-10 doi: 10.11847/zgggws1148796
Outline
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Objective

To compare the accuracy of multiple large language models (LLM) and manual judgment in predicting infectious disease trends.

Methods

Using monthly report data of 17 infectious diseases in Guangzhou from January to December 2024, we used five LLM and expert judgments from public health physicians for prediction and compared the predicted results with actual trends.

Results

A total of 99 predictions were conducted for 17 infectious diseases. The accuracy rate of prediction by public health physicians was 84.85%, and that of the AI-integrated prediction was 73.74%. The prediction accuracy of AI products followed the trend of Kimi (70.71%), Doubao (68.69%), Lingxi (68.69%, parallel), ERNIE Bot (65.66%), and Deep Seek (63.64%). On the basis of 99 referred data items related to dengue fever, norovirus infection, hand-foot-mouth disease, pertussis, and influenza, in the identification of epidemic inflection points, public health physicians showed the accuracy of 50.0%, followed by Kimi (30.0%), AI integration (20.0%), and Doubao (20.0%, parallel); public health physicians showed the F1 score of 0.56, followed by Kimi (0.40), Doubao (0.38), and AI integration (0.27).

Conclusions

Currently, public health physicians have higher accuracy in predicting infectious disease trends than AI, especially in identifying the impacts of complex social factors.

artificial intelligence  /  public health  /  infectious disease  /  prediction  /  Guangzhou city
吴宇骞, 董淑文, 向欣荣, 李宗欣, 甘建哲, 秦鹏哲. 大语言模型在广州市法定传染病趋势预测中的应用:基于2024年监测资料. 中国公共卫生, 2026 , 42 (5) : 551 -555 . DOI: 10.11847/zgggws1148796
Yuqian WU, Shuwen DONG, Xinrong XIANG, Zongxin LI, Jianzhe GAN, Pengzhe QIN. Application of large language models in predicting trends of notifiable infectious diseases in Guangzhou: based on 2024 surveillance data[J]. Chinese Journal of Public Health, 2026 , 42 (5) : 551 -555 . DOI: 10.11847/zgggws1148796
Year 2026 volume 42 Issue 5
77
29
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Article Info
doi: 10.11847/zgggws1148796
  • Receive Date:2025-09-02
  • Online Date:2026-10-23
  • Published:2026-05-10
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History
  • Received:2025-09-02
  • Revised:2025-12-19
  • Accepted:2026-03-09
Affiliations
    Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510440, China

Corresponding:

QIN Pengzhe, E-mail:
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表12种不同金属材料的力学参数
科
Family
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Number of
genus
种数
Number of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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