Home Journals Articles Updates About
CN
image
收藏切换
Progress in the Application of Inorganic Sonosensitizers in Tumor Sonodynamic Therapy
收藏切换
Yali YANG1, Jihu NIE2, Nailin YANG2, Shumin SUN2, Liang CHENG2
Materials China | 2026, 45(10) : 1026 - 1038
Less
收藏切换
Materials China | 2026, 45(10): 1026-1038
• Comprehensive Review •
Progress in the Application of Inorganic Sonosensitizers in Tumor Sonodynamic Therapy
Full
Yali YANG1, Jihu NIE2, Nailin YANG2, Shumin SUN2, Liang CHENG2
Affiliations
  • 1.Analysis and Testing Center, Soochow University, Suzhou 215123, China
  • 2.Institute of Functional Nano & Soft Materials, Soochow University, Suzhou 215123, China
Published: 2026-10-20 doi: 10.7502/j.issn.1674-3962.202504025
Outline
收藏切换

As an emerging non-invasive tumor treatment technique, sonodynamic therapy (SDT) uses ultrasound to stimulate the generation of reactive oxygen species to kill cancer cells. It has attracted much attention due to its excellent tissue penetration, efficient therapeutic effect and low toxicity side effect. In recent years, the development of efficient and low toxicity sonosensitizers have become a research hotspot in this field. Inorganic sonosensitizers have shown great potential in the field of SDT due to their excellent stability, controllable physicochemical properties, multifunctional integration ability and tumor targeting ability. This review systematically summarizes the evolution of inorganic sonosensitizers and divides them into three generations: the first generation improves performance by optimizing material structure, the second generation focuses on regulating the tumor microenvironment to enhance SDT efficacy, and the third generation achieves synergistic therapy by regulating immune response. Finally, this review discusses the challenges currently faced by inorganic sonosensitizers and looks forward to future development directions.

sonodynamic therapy  /  inorganic sonosensitizers  /  electron-hole pairs  /  tumor microenvironment  /  immunotherapy
杨亚丽, 聂继虎, 杨乃霖, 孙淑敏, 程亮. 无机声敏剂在肿瘤声动力疗法中的研究进展. 中国材料进展, 2026 , 45 (10) : 1026 -1038 . DOI: 10.7502/j.issn.1674-3962.202504025
Yali YANG, Jihu NIE, Nailin YANG, Shumin SUN, Liang CHENG. Progress in the Application of Inorganic Sonosensitizers in Tumor Sonodynamic Therapy[J]. Materials China, 2026 , 45 (10) : 1026 -1038 . DOI: 10.7502/j.issn.1674-3962.202504025
Appendix
Less
Year 2026 volume 45 Issue 10
136
18
Cite this Article
BibTeX
Article Info
doi: 10.7502/j.issn.1674-3962.202504025
  • Receive Date：2025-04-24
  • Online Date：2026-10-16
  • Published：2026-10-20
Article Data
Affiliations
History
  • Received：2025-04-24
  • Revised：2025-09-10
Funding
Affiliations
    1.Analysis and Testing Center, Soochow University, Suzhou 215123, China
    2.Institute of Functional Nano & Soft Materials, Soochow University, Suzhou 215123, China
References
Share
https://castjournals.cast.org.cn/joweb/zgcljz/EN/10.7502/j.issn.1674-3962.202504025
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62662699(Operation and Technical Support)
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House