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Research progress on mechanism analysis and therapeutic strategies of liver regeneration
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Qiu-dan WANG, Li-juan CAO*
Acta Pharmaceutica Sinica | 2026, 61(8) : 2829 - 2839
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Acta Pharmaceutica Sinica | 2026, 61(8): 2829-2839
• Reviews •
Research progress on mechanism analysis and therapeutic strategies of liver regeneration
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Qiu-dan WANG, Li-juan CAO*
Affiliations
  • State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China
Published: 2026-08-12 doi: 10.16438/j.0513-4870.2026-0105
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As a core biological process for the repair of liver injury, liver regeneration represents a key breakthrough in the treatment of liver failure and end-stage liver disease. Its mechanistic complexity and therapeutic translation potential have long been research hotspots. In recent years, with the advancement of molecular biology and regenerative medicine technologies, significant progress has been made in liver regeneration research, including mechanistic elucidation, identification of regulatory targets, and development of therapeutic strategies. This article systematically reviews the molecular mechanisms and therapeutic strategies of liver regeneration, analyzes current research bottlenecks, and discusses future directions, aiming to provide a reference for scientific research and clinical applications in this field.

liver regeneration  /  molecular mechanism  /  signaling pathway  /  drug therapy  /  cell transplantation  /  hepatic progenitor cell  /  regenerative microenvironment
王秋丹, 曹丽娟. 肝再生机制解析与治疗策略的研究进展. 药学学报, 2026 , 61 (8) : 2829 -2839 . DOI: 10.16438/j.0513-4870.2026-0105
Qiu-dan WANG, Li-juan CAO. Research progress on mechanism analysis and therapeutic strategies of liver regeneration[J]. Acta Pharmaceutica Sinica, 2026 , 61 (8) : 2829 -2839 . DOI: 10.16438/j.0513-4870.2026-0105
Year 2026 volume 61 Issue 8
395
194
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doi: 10.16438/j.0513-4870.2026-0105
  • Receive Date:2026-01-23
  • Online Date:2026-09-21
  • Published:2026-08-12
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  • Received:2026-01-23
  • Revised:2026-04-20
Affiliations
    State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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