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This study employs silica gel column chromatography and thin-layer chromatography to study the chemical constituents of the effective substance groups from Artemisia ordosica, and analyze the spectral data of the separated compounds to determine their structures. Nine alkynes, including ordosin (1), capillene (2), capillin (3), capillinol (4), trans-dehydromatricaria ester (5), capillarin (6), o-hydroxycapillene (7), capillaridin (8), o-hydroxycapillin (9), and one dihydroflavone, 5-hydroxy-7,4′-dimethoxydihydroflavone (10), were isolated and identified from the effective substance groups of Artemisia ordosica. Among these, compound 1 is a new alkyne, while 2-4, 6, 8, and 9 were isolated for the first time from Artemisia ordosica. By examining the effects of compounds 1-4, 6, 8, and 9 on the release of nitric oxide (NO) in the culture medium of RAW264.7 macrophages induced by lipopolysaccharide (LPS), the inhibitory effect on inflammatory response was evaluated. The results revealed that compounds 1-4, 6, 8, and 9 exhibited NO inhibitory activity at a concentration of 10 μmol·L-1, with inhibition rates of 96.7%, 88.4%, 91.6%, 77.8%, 98.7%, 86.7% and 75.1%, respectively.
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| 科 Family | 属数 Number of genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) | 属 Genus | 种数 Number of species | 占总种数比例 Percentage of total species (%) |
|---|---|---|---|---|---|---|
| 鹅膏菌科Amanitaceae | 2 | 11 | 5.26 | 鹅膏菌属 Amanita | 10 | 4.78 |
| 小菇科 Mycenaceae | 2 | 12 | 5.74 | 丝盖伞属 Inocybe | 5 | 2.39 |
| 多孔菌科 Polyporaceae | 8 | 14 | 6.70 | 蜡蘑属 Laccaria | 5 | 2.39 |
| 红菇科 Russulaceae | 3 | 23 | 11.00 | 小皮伞属 Marasmius | 6 | 2.87 |
| 小菇属 Mycena | 11 | 5.26 | ||||
| 光柄菇属 Pluteus | 5 | 2.39 | ||||
| 红菇属 Russula | 17 | 8.13 | ||||
| 栓菌属 Trametes | 5 | 2.39 |
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