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Natural products containing 3-acyl tetramic acid and their bioactivities
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Yue TIAN, Xuan PAN*, Zhan-zhu LIU*
Acta Pharmaceutica Sinica | 2026, 61(2) : 365 - 387
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Acta Pharmaceutica Sinica | 2026, 61(2): 365-387
• Reviews •
Natural products containing 3-acyl tetramic acid and their bioactivities
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Yue TIAN, Xuan PAN*, Zhan-zhu LIU*
Affiliations
  • State Key Laboratory of Bioactive Substance and Function of Nature Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China
Published: 2026-02-12 doi: 10.16438/j.0513-4870.2025-1101
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Tetramic acid unit occurred in a large number of natural products, which normally exhibited antitumor, anti-ulcer, antibacterial, antiviral, and herbicidal activities. Their complex and diverse molecular structures as well as broad biological activities have attracted great attention from biochemists. This article reviewed the natural products with tetramic acid structures isolated since 2013, classified them based on their structures, and introduced their biological activities.

tetramic acid  /  natural product  /  biological activity
田越, 潘璇, 刘站柱. 含有特特拉姆酸结构的天然产物及其生物活性. 药学学报, 2026 , 61 (2) : 365 -387 . DOI: 10.16438/j.0513-4870.2025-1101
Yue TIAN, Xuan PAN, Zhan-zhu LIU. Natural products containing 3-acyl tetramic acid and their bioactivities[J]. Acta Pharmaceutica Sinica, 2026 , 61 (2) : 365 -387 . DOI: 10.16438/j.0513-4870.2025-1101
Year 2026 volume 61 Issue 2
291
155
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Article Info
doi: 10.16438/j.0513-4870.2025-1101
  • Receive Date:2025-09-17
  • Online Date:2026-09-21
  • Published:2026-02-12
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  • Received:2025-09-17
  • Revised:2025-10-31
Affiliations
    State Key Laboratory of Bioactive Substance and Function of Nature Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数
科
Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)
属
Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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