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A pair of new diarylheptanoid enantiomers from bulbils of Dioscorea opposite Thunb.
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Yan-gang CAO1, 2, Meng-huan GUO1, 2, Yi-xin ZHAO1, 2, Yan-ling LIU1, 2, Xu CHEN1, 2, Xiao-ke ZHENG1, 2, *, Wei-sheng FENG1, 2, *
Acta Pharmaceutica Sinica | 2025, 60(10) : 3146 - 3151
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Acta Pharmaceutica Sinica | 2025, 60(10): 3146-3151
• Original Articles •
A pair of new diarylheptanoid enantiomers from bulbils of Dioscorea opposite Thunb.
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Yan-gang CAO1, 2, Meng-huan GUO1, 2, Yi-xin ZHAO1, 2, Yan-ling LIU1, 2, Xu CHEN1, 2, Xiao-ke ZHENG1, 2, *, Wei-sheng FENG1, 2, *
Affiliations
  • 1School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China
  • 2The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou 450046, China
Published: 2025-10-12 doi: 10.16438/j.0513-4870.2025-0545
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Nine compounds were isolated and identified as (±)-diosniponol G (1), neo-olivil (2), isolariciresinol (3), bombasin (4), isoschaftoside (5), saponarin (6), apigenin 6-C-α-L-arabinopyranosyl-7-O-β-D-glucopyranoside (7), 2-hydroxy-3, 5, 7-trimethoxy-9, 10-dihydrophenanthrene (8), and albibrissinoside B (9) from bulbils of Dioscorea opposite Thunb. by multiple column chromatographic methods including Diaion HP-20, MCI gel CHP-20, and Sephadex LH-20. Compound 1 was a new pair of diarylheptanoid enantiomers, and the other compounds were isolated from D. opposite for the first time. The α-glucosidase inhibitory activities of the isolates were screened, and no compound exhibited significantly inhibitory activity against α-glucosidase at the concentration of 100 μmol·L-1.

bulbils of Dioscorea opposite Thunb.  /  Dioscoreaceae  /  isolation and identification  /  diarylheptanoid
曹彦刚, 郭孟焕, 赵怡欣, 刘晏灵, 陈旭, 郑晓珂, 冯卫生. 零余子中一对新的二苯基庚烷对映体. 药学学报, 2025 , 60 (10) : 3146 -3151 . DOI: 10.16438/j.0513-4870.2025-0545
Yan-gang CAO, Meng-huan GUO, Yi-xin ZHAO, Yan-ling LIU, Xu CHEN, Xiao-ke ZHENG, Wei-sheng FENG. A pair of new diarylheptanoid enantiomers from bulbils of Dioscorea opposite Thunb.[J]. Acta Pharmaceutica Sinica, 2025 , 60 (10) : 3146 -3151 . DOI: 10.16438/j.0513-4870.2025-0545
Appendix
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Year 2025 volume 60 Issue 10
285
131
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Article Info
doi: 10.16438/j.0513-4870.2025-0545
  • Receive Date：2025-05-12
  • Online Date：2026-09-20
  • Published：2025-10-12
Article Data
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History
  • Received：2025-05-12
  • Revised：2025-07-17
Affiliations
    1School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, China
    2The Engineering and Technology Center for Chinese Medicine Development of Henan Province, Zhengzhou 450046, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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