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Modern research approaches and strategies for compatibility effects and efficacy components of herbal pairs
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Yu-ping TANG1, *, Er-xin SHANG2, Yan-yan CHEN1, Shi-jun YUE1, Xu-qin SHI2, T. X. Tina DONG3, W. K. Karl TSIM3, Jin-ao DUAN2
Acta Pharmaceutica Sinica | 2019, 54(9) : 1564 - 1573
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Acta Pharmaceutica Sinica | 2019, 54(9): 1564-1573
• Reviews •
Modern research approaches and strategies for compatibility effects and efficacy components of herbal pairs
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Yu-ping TANG1, *, Er-xin SHANG2, Yan-yan CHEN1, Shi-jun YUE1, Xu-qin SHI2, T. X. Tina DONG3, W. K. Karl TSIM3, Jin-ao DUAN2
Affiliations
  • 1. Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility, and State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources(Cultivation), and Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, and Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an 712046, China
  • 2. Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization/National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine/Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing 210023, China
  • 3. Division of Life Science and Centre for Chinese Medicine, the Hongkong University of Science and Technology, Hongkong 999077, China
Published: 2019-09-12 doi: 10.16438/j.0513-4870.2019-0413
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The herb pair is the simple and exquisite experience summary accumulated by generations of traditional Chinese medicine (TCM) experts in the process of long-term herbal prescription for curing diseases. Although it is only a combination of two herbs, it is cleverly matched and properly proportioned, which can well interpret TCM characteristics of "great combination and artful application". Moreover, the herb pair is an intermediate point between single herb and several TCM formulae, which implicates certain regularity and some connotation of many TCM formulae for diagnosis and treatment based on an overall analysis of the illness and the patient's condition. Our team has long been focusing on the complexity of drug interactions and the diversity of TCM components to carry out systematic research on herb pair by using modern scientific and technological knowledge and approaches. As results, a series of modern research approaches and strategies formed for the compatibility effect and bio-active components of the herb pair. By representing the principles and application characteristics of these approaches, this paper provides important support for elucidating scientific connotation of compatibility regularity of herb pairs and application of formulae optimization, as well as explorative ideas and approaches for modern research on other herb pairs.

herb pair  /  compatibility effect  /  efficacy component  /  drug interaction  /  modern research
Yu-ping TANG, Er-xin SHANG, Yan-yan CHEN, Shi-jun YUE, Xu-qin SHI, T. X. Tina DONG, W. K. Karl TSIM, Jin-ao DUAN. Modern research approaches and strategies for compatibility effects and efficacy components of herbal pairs[J]. Acta Pharmaceutica Sinica, 2019 , 54 (9) : 1564 -1573 . DOI: 10.16438/j.0513-4870.2019-0413
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Article Info
doi: 10.16438/j.0513-4870.2019-0413
  • Receive Date：2019-05-28
  • Online Date：2026-01-26
  • Published：2019-09-12
Article Data
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History
  • Received：2019-05-28
  • Revised：2019-06-28
Funding
Affiliations
    1. Key Laboratory of Shaanxi Administration of Traditional Chinese Medicine for TCM Compatibility, and State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources(Cultivation), and Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, and Shaanxi Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Shaanxi University of Chinese Medicine, Xi'an 712046, China
    2. Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization/National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine/Jiangsu Key Laboratory for High Technology Research of TCM Formulae, Nanjing University of Chinese Medicine, Nanjing 210023, China
    3. Division of Life Science and Centre for Chinese Medicine, the Hongkong University of Science and Technology, Hongkong 999077, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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