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Research progress about the anti-aging effect and mechanism of flavonoids from traditional Chinese medicine
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Meng-ru LI1, Yu-zhi ZHOU1, *, Guan-hua DU1, 2, Xue-mei QIN1, *
Acta Pharmaceutica Sinica | 2019, 54(8) : 1382 - 1391
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Acta Pharmaceutica Sinica | 2019, 54(8): 1382-1391
• Reviews •
Research progress about the anti-aging effect and mechanism of flavonoids from traditional Chinese medicine
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Meng-ru LI1, Yu-zhi ZHOU1, *, Guan-hua DU1, 2, Xue-mei QIN1, *
Affiliations
  • 1. Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China
  • 2. Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China
Published: 2019-08-12 doi: 10.16438/j.0513-4870.2019-0283
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Aging is a normal physiological process involving coaction of many factors. The anti-aging effects of natural products have been studied by many domestic and international scholars, but not far enough, which still needed to be explored. Flavonoids, as natural products, have a variety of pharmacological activities and present in many traditional Chinese medicines. In recent years, research results indicate that flavonoids can delay the aging process of the nervous, immune, and reproductive systems, and the liver, skin and other tissues. The anti-aging effects of flavonoids have attracted more and more attention. Therefore, development of anti-aging drugs from flavonoids is of great significance to improve the quality of life for the elderly and slow the process of aging. However, the mechanism of the anti-aging effect of flavonoids remains unknown at present. This review will discuss the anti-aging effect and mechanisms of flavonoids in traditional Chinese medicine from the aspects of cellular signaling pathways and metabolic pathways based on the modern theories of aging.

flavonoids  /  antioxidant  /  anti-aging  /  free radical theory  /  cellular signaling pathway  /  metabolic pathway
Meng-ru LI, Yu-zhi ZHOU, Guan-hua DU, Xue-mei QIN. Research progress about the anti-aging effect and mechanism of flavonoids from traditional Chinese medicine[J]. Acta Pharmaceutica Sinica, 2019 , 54 (8) : 1382 -1391 . DOI: 10.16438/j.0513-4870.2019-0283
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Article Info
doi: 10.16438/j.0513-4870.2019-0283
  • Receive Date：2019-04-16
  • Online Date：2026-01-26
  • Published：2019-08-12
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  • Received：2019-04-16
  • Revised：2019-05-30
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Affiliations
    1. Modern Research Center for Traditional Chinese Medicine, Shanxi University, Taiyuan 030006, China
    2. Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China
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表12种不同金属材料的力学参数
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Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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