Home Journals Articles Updates About
CN
image
收藏切换
Discovery of quality markers of traditional Chinese medicine compounds and visualization technology of content-effect colour atla
收藏切换
PDF
Xian-sheng MENG1, 2, 3, *, Yong-rui BAO1, 2, 3, Shuai WANG1, 2, 3, Tian-jiao LI1, 2, 3, Guo-an LUO4
Acta Pharmaceutica Sinica | 2019, 54(2) : 222 - 227
Less
收藏切换
Acta Pharmaceutica Sinica | 2019, 54(2): 222-227
• Special Reports: The Quality and Quality Markers of Traditional Chinese Medicine •
Discovery of quality markers of traditional Chinese medicine compounds and visualization technology of content-effect colour atla
Full
Xian-sheng MENG1, 2, 3, *, Yong-rui BAO1, 2, 3, Shuai WANG1, 2, 3, Tian-jiao LI1, 2, 3, Guo-an LUO4
Affiliations
  • 1. School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China
  • 2. Province Multi-Component Chinese Medicine Engineering Technology Research Center of Liaoning, Dalian 116600, China
  • 3. Modern Traditional Chinese Medicine Research and Engineering Laboratory of Liaoning, Dalian 116600, China
  • 4. Department of Chemistry, Tsinghua University, Beijing 100084, China
Published: 2019-02-12 doi: 10.16438/j.0513-4870.2018-0775
Outline
收藏切换

The chemical composition of traditional Chinese medicine (TCM) compounds is complex, the treatment is broad, and the quality control indexes cannot accurately reflect the functional properties. According to the above problems, the authors take the research process of quality markers of Qizhiweitong granules as an example to innovate the research ideas and technical methods, and constructed five progressive steps of TCM compounds quality control and evaluation model:"based on function, to figure out the attending", "components and pharmacodynamics correlation, multiple components with multiple effects", "to analyze the components, and systematically integrate them", "spectrum and effect correlation, from a spectrum to see the efficiency", and "from the content-effect colour atla to see the quality". Based on the multiple effects of components, multiple components of multi-effect pharmacological efficacy evaluation system were established. All-time isobaric multiwavelength fusion fingerprint technology was improved and developed. "Spectrum-effect colour atla" software was research and developed for the first time, to realize the "visualization" of TCM efficacy. The aim of this work is to provide an exploratory solution for the integrated quality control of TCM compounds.

traditional Chinese medicine compound  /  quality marker  /  spectrum-effect relationship  /  content-effect colour atla
Xian-sheng MENG, Yong-rui BAO, Shuai WANG, Tian-jiao LI, Guo-an LUO. Discovery of quality markers of traditional Chinese medicine compounds and visualization technology of content-effect colour atla[J]. Acta Pharmaceutica Sinica, 2019 , 54 (2) : 222 -227 . DOI: 10.16438/j.0513-4870.2018-0775
Appendix
Less
Year 2019 volume 54 Issue 2
PDF
153
65
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2018-0775
  • Receive Date：2018-08-24
  • Online Date：2026-01-26
  • Published：2019-02-12
Article Data
Affiliations
History
  • Received：2018-08-24
  • Revised：2018-10-22
Funding
Affiliations
    1. School of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China
    2. Province Multi-Component Chinese Medicine Engineering Technology Research Center of Liaoning, Dalian 116600, China
    3. Modern Traditional Chinese Medicine Research and Engineering Laboratory of Liaoning, Dalian 116600, China
    4. Department of Chemistry, Tsinghua University, Beijing 100084, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2018-0775
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House