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Applications of ionic liquids in drug research
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Jian-ping CAO, Yong-xiao MOU, Yuan-yuan CHEN, Tao WEI, Chao-jie WANG*
Acta Pharmaceutica Sinica | 2019, 54(2) : 245 - 257
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Acta Pharmaceutica Sinica | 2019, 54(2): 245-257
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Applications of ionic liquids in drug research
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Jian-ping CAO, Yong-xiao MOU, Yuan-yuan CHEN, Tao WEI, Chao-jie WANG*
Affiliations
  • School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China
Published: 2019-02-12 doi: 10.16438/j.0513-4870.2018-0761
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Ionic liquids are not limited to the traditional use of solvents because of their high permeability and excellent physicochemical and unique biological properties. Nowadays, with the deep understanding of their toxicity and biocompatibility, ionic liquids have been tailored as novel solutions to address potential problems of marketed drugs. Based on the research and development of modified new drugs, ionic liquids have been incorporated into drug synthesis and emerged as attractive environmental-friendly reaction media with milder reaction conditions, higher yields and easier reaction workups and drug delivery systems. In addition, they have been designed for effective drug carriers removing undesirable properties of solid drugs. Further, ionic liquids forming active pharmaceutical ingredients dedicated to the liquefaction of drugs for promising clinical applications.

ionic liquid  /  drug synthesis  /  drug delivery  /  active pharmaceutical ingredient  /  clinical application
Jian-ping CAO, Yong-xiao MOU, Yuan-yuan CHEN, Tao WEI, Chao-jie WANG. Applications of ionic liquids in drug research[J]. Acta Pharmaceutica Sinica, 2019 , 54 (2) : 245 -257 . DOI: 10.16438/j.0513-4870.2018-0761
Year 2019 volume 54 Issue 2
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Article Info
doi: 10.16438/j.0513-4870.2018-0761
  • Receive Date:2018-08-19
  • Online Date:2026-01-26
  • Published:2019-02-12
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  • Received:2018-08-19
  • Revised:2018-10-08
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    School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou 325035, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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