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A new cadinane-type sesquiterpenoid from Eupatorium adenophorum Spreng
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Xu LIANG1, Xin-zhou YANG2, Chao-qun Wu2, Yu-zhao LI2, Jing-quan YUAN1, *
Acta Pharmaceutica Sinica | 2020, 55(12) : 2955 - 2959
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Acta Pharmaceutica Sinica | 2020, 55(12): 2955-2959
• Original Articles •
A new cadinane-type sesquiterpenoid from Eupatorium adenophorum Spreng
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Xu LIANG1, Xin-zhou YANG2, Chao-qun Wu2, Yu-zhao LI2, Jing-quan YUAN1, *
Affiliations
  • 1. Guangxi University of Chinese Medicine, Nanning 530200, China
  • 2. School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China
Published: 2020-12-12 doi: 10.16438/j.0513-4870.2020-1302
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Four cadinane-type sesquiterpenes were obtained from the petroleum ether of 95% ethanol extract of Eupatorium adenophorum Spreng by using an HP-20 macroporous resin column, silica gel, and semi-preparative HPLC. Their structures were determined by physical, chemical and spectroscopic methods and identified as eupatorinol (1), (+)-(5R, 7S, 9R, 10S)-2-oxocadinan-3, 6(11)-dien-12, 7-olide (2), (1S, 4R)-7-hydroxycalamenen-3-one(3) and (-)-(5R, 6R, 7S, 9R, 10S)-cadinan-3-ene-6, 7-diol (4). Among them, compound 1 is a new cadinane-type sesquiterpene, and compound 3 was isolated from this genus for the first time. In bioassay, none of these compounds displayed obvious cytotoxicity.

Eupatorium adenophorum Spreng  /  chemical constituent  /  cadinane-type sesquiterpenoid  /  alien invasive plant
Xu LIANG, Xin-zhou YANG, Chao-qun Wu, Yu-zhao LI, Jing-quan YUAN. A new cadinane-type sesquiterpenoid from Eupatorium adenophorum Spreng[J]. Acta Pharmaceutica Sinica, 2020 , 55 (12) : 2955 -2959 . DOI: 10.16438/j.0513-4870.2020-1302
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Article Info
doi: 10.16438/j.0513-4870.2020-1302
  • Receive Date：2020-08-07
  • Online Date：2026-01-23
  • Published：2020-12-12
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  • Received：2020-08-07
  • Revised：2020-08-26
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    1. Guangxi University of Chinese Medicine, Nanning 530200, China
    2. School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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