收藏切换
Progress and perspective of potential anti-coronavirus activity of phenothiazines
收藏切换
PDF
Jun-yue WAN1, Hua CHEN2, *, Jie YIN2
Acta Pharmaceutica Sinica | 2020, 55(11) : 2529 - 2534
Less
收藏切换
Acta Pharmaceutica Sinica | 2020, 55(11): 2529-2534
Reviews
Progress and perspective of potential anti-coronavirus activity of phenothiazines
Full
Jun-yue WAN1, Hua CHEN2, *, Jie YIN2
Affiliations
  • 1. China Pharmaceutical University, Nanjing 210000, China
  • 2. NMPA Key Laboratory for Quality Research and Evaluation of Chemical Drugs, National Institutes for Food and Drug Control, Beijing 100050, China
Published: 2020-11-12 doi: 10.16438/j.0513-4870.2020-0554
Outline
收藏切换

Coronaviruses (CoVs) are associated with some mammalian infectious diseases, which have caused several outbreaks of respiratory system infectious diseases in recent years. There is no effective vaccine or approved drug treatment against coronaviruses, and the development of anti-coronavirus agents is an urgent priority. Phenothiazines are a class of antipsychotic drugs, which were found that they have some other biological activities, like promising antibacterial, antifungal, anticancer, antiviral, etc. They can be used for drug repurposing. This review summarizes current researches on the potential anti-coronavirus activity of phenothiazine, discusses the mechanisms and some research difficulties, and provides a foundation for developing anti-coronavirus drugs which use phenothiazine as the lead compound.

coronavirus  /  novel coronavirus  /  phenothiazine  /  antiviral agent  /  antipsychotic agent
Jun-yue WAN, Hua CHEN, Jie YIN. Progress and perspective of potential anti-coronavirus activity of phenothiazines[J]. Acta Pharmaceutica Sinica, 2020 , 55 (11) : 2529 -2534 . DOI: 10.16438/j.0513-4870.2020-0554
Year 2020 volume 55 Issue 11
PDF
124
49
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2020-0554
  • Receive Date:2020-04-16
  • Online Date:2026-01-23
  • Published:2020-11-12
Article Data
Affiliations
History
  • Received:2020-04-16
  • Revised:2020-05-26
Affiliations
    1. China Pharmaceutical University, Nanjing 210000, China
    2. NMPA Key Laboratory for Quality Research and Evaluation of Chemical Drugs, National Institutes for Food and Drug Control, Beijing 100050, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2020-0554
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT