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Metabolism and pharmacokinetics of drugs applied for the treatment of Corona Virus Disease 2019 (COVID-19)
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Lu-lu PAN, Da-fang ZHONG*
Acta Pharmaceutica Sinica | 2020, 55(11) : 2570 - 2579
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Acta Pharmaceutica Sinica | 2020, 55(11): 2570-2579
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Metabolism and pharmacokinetics of drugs applied for the treatment of Corona Virus Disease 2019 (COVID-19)
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Lu-lu PAN, Da-fang ZHONG*
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  • Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
Published: 2020-11-12 doi: 10.16438/j.0513-4870.2020-0696
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Based on Chinese clinical guidance for COVID-19 pneumonia diagnosis and treatment (7th edition), the metabolism and pharmacokinetics of drugs used in clinical treatment of COVID-19 were reviewed. The antiviral drugs include remdesivir, chloroquine/hydroxychloroquine, lopinavir/ritonavir, favipiravir, arbidol, baicalin, baicalein and forsythin. Among them, the metabolism and pharmacokinetics of arbidol, baicalin and forsythin are the research results of the author's laboratory. This article aims to provide reference for the efficacy evaluation and rational drug use of COVID-19.

COVID-19  /  metabolism  /  pharmacokinetics
Lu-lu PAN, Da-fang ZHONG. Metabolism and pharmacokinetics of drugs applied for the treatment of Corona Virus Disease 2019 (COVID-19)[J]. Acta Pharmaceutica Sinica, 2020 , 55 (11) : 2570 -2579 . DOI: 10.16438/j.0513-4870.2020-0696
Year 2020 volume 55 Issue 11
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doi: 10.16438/j.0513-4870.2020-0696
  • Receive Date:2020-05-07
  • Online Date:2026-01-23
  • Published:2020-11-12
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  • Received:2020-05-07
  • Revised:2020-05-27
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    Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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