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Application of dithiocarbamates and their derivatives in medicinal chemistry
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Jie GUO1, Zhi-peng ZHANG1, Mao-jun CHENG1, Jing LIU2, Wei-xin ZHOU1, Sai-sai XIE1, *
Acta Pharmaceutica Sinica | 2020, 55(10) : 2330 - 2339
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Acta Pharmaceutica Sinica | 2020, 55(10): 2330-2339
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Application of dithiocarbamates and their derivatives in medicinal chemistry
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Jie GUO1, Zhi-peng ZHANG1, Mao-jun CHENG1, Jing LIU2, Wei-xin ZHOU1, Sai-sai XIE1, *
Affiliations
  • 1. National Pharmaceutical Engineering Research Center for Solid Preparation in Chinese Herbal Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China
  • 2. School of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China
Published: 2020-10-12 doi: 10.16438/j.0513-4870.2020-0588
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Dithiocarbamates and their derivatives with unique molecular structures possess diverse biological activities, which have become the research focus in the chemical and pharmaceutical fields in recent years. Here, we will review the structures, synthesis as well as biological activities of dithiocarbamates and their derivatives in anti-oxidation, anti-virus, anti-bacterial, anti-tumor and anti-Alzheimer's disease, and make a prospect for their development in the future.

dithiocarbamates  /  structure  /  synthesis  /  biological activity  /  prospect
Jie GUO, Zhi-peng ZHANG, Mao-jun CHENG, Jing LIU, Wei-xin ZHOU, Sai-sai XIE. Application of dithiocarbamates and their derivatives in medicinal chemistry[J]. Acta Pharmaceutica Sinica, 2020 , 55 (10) : 2330 -2339 . DOI: 10.16438/j.0513-4870.2020-0588
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Article Info
doi: 10.16438/j.0513-4870.2020-0588
  • Receive Date：2020-04-20
  • Online Date：2026-01-23
  • Published：2020-10-12
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History
  • Received：2020-04-20
  • Revised：2020-05-25
Funding
Affiliations
    1. National Pharmaceutical Engineering Research Center for Solid Preparation in Chinese Herbal Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China
    2. School of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, China
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表12种不同金属材料的力学参数
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Family		 属数
Number of
genus		 种数
Number of
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Percentage of
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鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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