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Recent research progress on galectin-3 as a potential therapeutic target in respiratory diseases
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Rong SI, Ming-han CHENG, Jian GAO*
Acta Pharmaceutica Sinica | 2020, 55(7) : 1401 - 1409
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Acta Pharmaceutica Sinica | 2020, 55(7): 1401-1409
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Recent research progress on galectin-3 as a potential therapeutic target in respiratory diseases
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Rong SI, Ming-han CHENG, Jian GAO*
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  • The Second Affiliated Hospital, School of Pharmacy, Dalian Medical University, Dalian 116023, China
Published: 2020-07-12 doi: 10.16438/j.0513-4870.2020-0581
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Galectin-3 is an endogenous β-galactoside-binding lectin widely distributed in the human body, and it plays an important role in various functions such as cell proliferation, differentiation, apoptosis, cell adhesion, immune response and signal transduction. Accumulating evidence has shown that galectin-3 is involved in the occurrence and development of respiratory diseases, including idiopathic pulmonary fibrosis, lung cancer, pulmonary hypertension and bronchial asthma. This review summarizes and analyzes the research progress on galectin-3 in the above respiratory diseases in order to clarify its role and mechanism, and to provide new ideas for clinical treatment.

galectin-3  /  idiopathic pulmonary fibrosis  /  lung cancer  /  pulmonary arterial hypertension  /  bronchial asthma
Rong SI, Ming-han CHENG, Jian GAO. Recent research progress on galectin-3 as a potential therapeutic target in respiratory diseases[J]. Acta Pharmaceutica Sinica, 2020 , 55 (7) : 1401 -1409 . DOI: 10.16438/j.0513-4870.2020-0581
Year 2020 volume 55 Issue 7
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Article Info
doi: 10.16438/j.0513-4870.2020-0581
  • Receive Date:2020-04-20
  • Online Date:2026-01-21
  • Published:2020-07-12
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  • Received:2020-04-20
  • Accepted:2020-05-29
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    The Second Affiliated Hospital, School of Pharmacy, Dalian Medical University, Dalian 116023, China
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表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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