收藏切换
Progress on the discovery and development of anti-zika virus agents
收藏切换
PDF
Zhuo LI, Rui-fang JIA, Peng ZHAN*, Xin-yong LIU*
Acta Pharmaceutica Sinica | 2020, 55(4) : 627 - 639
Less
收藏切换
Acta Pharmaceutica Sinica | 2020, 55(4): 627-639
Reviews
Progress on the discovery and development of anti-zika virus agents
Full
Zhuo LI, Rui-fang JIA, Peng ZHAN*, Xin-yong LIU*
Affiliations
  • Department of Medicinal Chemistry, Key Laboratory of Chemical Biology(Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
Published: 2020-04-12 doi: 10.16438/j.0513-4870.2019-0748
Outline
收藏切换

Zika virus (ZIKV) is a kind of mosquito-borne flavivirus. ZIKV infection initially shows mild symptoms on patients, but will lead to severe neurological complications (such as Guillain-Barré syndrome) in the end. Meanwhile, pregnant women are sensitive to ZIKV, since the viruses may cause microcephaly. In 2015, after the epidemic in Brazil, ZIKV draws the public attention around the world because of its increased virulence and rapid dissemination. However, there is no approved specific anti-ZIKV drugs at present. This review summarizes progress on anti-zika virus drug research and provides prospects in this field.

Zika virus  /  antiviral agent  /  small molecule  /  virus target  /  host target  /  drug design
Zhuo LI, Rui-fang JIA, Peng ZHAN, Xin-yong LIU. Progress on the discovery and development of anti-zika virus agents[J]. Acta Pharmaceutica Sinica, 2020 , 55 (4) : 627 -639 . DOI: 10.16438/j.0513-4870.2019-0748
Year 2020 volume 55 Issue 4
PDF
152
61
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2019-0748
  • Receive Date:2019-09-11
  • Online Date:2026-01-20
  • Published:2020-04-12
Article Data
Affiliations
History
  • Received:2019-09-11
  • Revised:2019-10-08
Funding
Affiliations
    Department of Medicinal Chemistry, Key Laboratory of Chemical Biology(Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2019-0748
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数

Family
属数
Number of
genus
种数
Number of
species
占总种数比例
Percentage of
total species (%)

Genus
种数
Number of
species
占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT