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Recent advances in the discovery and development of Ebola virus inhibitors
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Yu-jie REN, Shuo ZHANG, Fen-ju WEI, Xin-yong LIU*, Peng ZHAN*
Acta Pharmaceutica Sinica | 2020, 55(4) : 694 - 702
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Acta Pharmaceutica Sinica | 2020, 55(4): 694-702
• Reviews •
Recent advances in the discovery and development of Ebola virus inhibitors
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Yu-jie REN, Shuo ZHANG, Fen-ju WEI, Xin-yong LIU*, Peng ZHAN*
Affiliations
  • Department of Medicinal Chemistry, Key Laboratory of Chemical Biology(Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
Published: 2020-04-12 doi: 10.16438/j.0513-4870.2019-0859
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Ebola virus is extremely virulent and highly contagious. Ebola virus causes outbreaks of severe hemorrhagic fever, with human mortality rates of up to 90%. There is currently no preventive or therapeutic treatment in the form of vaccines, biological or small molecular agents. Currently, a lot of anti-Ebola virus agents have been reported. Here, we review the latest advances in this field.

Ebola virus  /  filovirus  /  antiviral  /  inhibitor  /  small molecule
Yu-jie REN, Shuo ZHANG, Fen-ju WEI, Xin-yong LIU, Peng ZHAN. Recent advances in the discovery and development of Ebola virus inhibitors[J]. Acta Pharmaceutica Sinica, 2020 , 55 (4) : 694 -702 . DOI: 10.16438/j.0513-4870.2019-0859
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Article Info
doi: 10.16438/j.0513-4870.2019-0859
  • Receive Date：2019-10-30
  • Online Date：2026-01-20
  • Published：2020-04-12
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  • Received：2019-10-30
  • Revised：2019-11-21
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Affiliations
    Department of Medicinal Chemistry, Key Laboratory of Chemical Biology(Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
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表12种不同金属材料的力学参数
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小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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