Home Journals Articles Updates About
CN
image
收藏切换
Progress on IFV drug targets and small molecule inhibitors
收藏切换
PDF
Si-yu XIU1, Jian ZHANG1, Han JU1, Rui-fang JIA1, Bing HUANG2, Peng ZHAN1, *, Xin-yong LIU1, *
Acta Pharmaceutica Sinica | 2020, 55(4) : 611 - 626
Less
收藏切换
Acta Pharmaceutica Sinica | 2020, 55(4): 611-626
• Reviews •
Progress on IFV drug targets and small molecule inhibitors
Full
Si-yu XIU1, Jian ZHANG1, Han JU1, Rui-fang JIA1, Bing HUANG2, Peng ZHAN1, *, Xin-yong LIU1, *
Affiliations
  • 1. Department of Medicinal Chemistry, Key Laboratory of Chemical Biology(Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
  • 2. Institute of Poultry Science, Shandong Academy of Agricultural Sciences, Jinan 250012, China
Published: 2020-04-12 doi: 10.16438/j.0513-4870.2019-0737
Outline
收藏切换

The outbreak of the influenza viruses (IFV) caused significant harm to our health and life. Human infections caused by pathogenic avian influenza virus (AIV) have continually brought great panic and death threats to people all over the world. With the in-depth study of the biological characteristics of influenza viruses and the rapid development of drug discovery screening technology, a new generation of anti-influenza drug targets and their inhibitors have been continuously discovered, providing more options for the treatment of influenza. From the point of view of medicinal chemistry, this review summarizes and discusses current endeavours towards the discovery and development of novel inhibitors and also provides examples illustrating new methodologies that contribute to the identification of novel anti-influenza drugs.

influenza virus  /  antiviral drug  /  drug target  /  drug design  /  small molecule inhibitor
Si-yu XIU, Jian ZHANG, Han JU, Rui-fang JIA, Bing HUANG, Peng ZHAN, Xin-yong LIU. Progress on IFV drug targets and small molecule inhibitors[J]. Acta Pharmaceutica Sinica, 2020 , 55 (4) : 611 -626 . DOI: 10.16438/j.0513-4870.2019-0737
Appendix
Less
Year 2020 volume 55 Issue 4
PDF
176
72
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2019-0737
  • Receive Date：2019-09-09
  • Online Date：2026-01-20
  • Published：2020-04-12
Article Data
Affiliations
History
  • Received：2019-09-09
  • Revised：2019-10-09
Funding
Affiliations
    1. Department of Medicinal Chemistry, Key Laboratory of Chemical Biology(Ministry of Education), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
    2. Institute of Poultry Science, Shandong Academy of Agricultural Sciences, Jinan 250012, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2019-0737
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House