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Advance in relationship between receptor gene abnormality and depression
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Hui-qin WANG1, 2, Zhen-zhen WANG2, Nai-hong CHEN1, 2, *
Acta Pharmaceutica Sinica | 2020, 55(3) : 384 - 391
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Acta Pharmaceutica Sinica | 2020, 55(3): 384-391
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Advance in relationship between receptor gene abnormality and depression
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Hui-qin WANG1, 2, Zhen-zhen WANG2, Nai-hong CHEN1, 2, *
Affiliations
  • 1. Hunan Engineering Technology Center of Standardization and Function of Chinese Herbal Decoction Pieces, College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
  • 2. Neuroscience Center, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China
Published: 2020-03-12 doi: 10.16438/j.0513-4870.2019-0600
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Depression, a chronic syndrome with low mood, pessimism, cognitive and sleep disorders, is characterized by high incidence, high suicide rate, low consultation and treatment rate. 40%-50% of the risk of depression comes from genes, so studying on gene abnormalities serves as an important part of the research in the internal causes of depression, among which the receptor gene abnormalities are crucial factors. The study of potential receptor gene loci is expected to be new target for the treatment of depression in the future, which can provide theoretical basis for the early diagnosis, prevention and treatment of depression.

depression  /  receptor  /  receptor gene  /  gene abnormality  /  pathogenesis
Hui-qin WANG, Zhen-zhen WANG, Nai-hong CHEN. Advance in relationship between receptor gene abnormality and depression[J]. Acta Pharmaceutica Sinica, 2020 , 55 (3) : 384 -391 . DOI: 10.16438/j.0513-4870.2019-0600
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Article Info
doi: 10.16438/j.0513-4870.2019-0600
  • Receive Date：2019-07-25
  • Online Date：2026-01-20
  • Published：2020-03-12
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History
  • Received：2019-07-25
  • Revised：2019-10-08
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Affiliations
    1. Hunan Engineering Technology Center of Standardization and Function of Chinese Herbal Decoction Pieces, College of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China
    2. Neuroscience Center, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China
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多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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