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A new carbazole alkaloid from the stems of Clausena lansium
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Jie MA1, Xing-yan SUN1, Ying-da ZANG1, Jian-zhou MENG2, Chuang-jun LI1, Jing-zhi YANG1, Dong-ming ZHANG1, *
Acta Pharmaceutica Sinica | 2020, 55(1) : 110 - 112
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Acta Pharmaceutica Sinica | 2020, 55(1): 110-112
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A new carbazole alkaloid from the stems of Clausena lansium
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Jie MA1, Xing-yan SUN1, Ying-da ZANG1, Jian-zhou MENG2, Chuang-jun LI1, Jing-zhi YANG1, Dong-ming ZHANG1, *
Affiliations
  • 1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
  • 2. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
Published: 2020-01-12 doi: 10.16438/j.0513-4870.2019-0744
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A new carbazole alkaloid was isolated from the aqueous extract of the stems of Clausena lansium (Lour.) Skeels by various chromatographic methods, including HPD-100, PRP-512A, silica gel, and reverse phase C18. Its structure was determined by spectroscopic and chemical methods, including UV, IR, HR-ESI-MS, 1D/2DNMR and ECD. Compound 1, named as Claulamine F, showed no antimicrobial activity on Staphylococcus aureus, Escherichia coli or Pseudomonas aeruginosa. In addition, compound 1 exhibited no cytotoxicity on five kinds of cancer cells through MTT methods.

Clausena lansium (Lour.) Skeels  /  chemical constituent  /  carbazole alkaloid  /  antimicrobial  /  cytotoxicity
Jie MA, Xing-yan SUN, Ying-da ZANG, Jian-zhou MENG, Chuang-jun LI, Jing-zhi YANG, Dong-ming ZHANG. A new carbazole alkaloid from the stems of Clausena lansium[J]. Acta Pharmaceutica Sinica, 2020 , 55 (1) : 110 -112 . DOI: 10.16438/j.0513-4870.2019-0744
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Article Info
doi: 10.16438/j.0513-4870.2019-0744
  • Receive Date：2019-09-11
  • Online Date：2026-01-20
  • Published：2020-01-12
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History
  • Received：2019-09-11
  • Revised：2019-10-10
Funding
Affiliations
    1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
    2. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
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表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
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