Home Journals Articles Updates About
CN
image
收藏切换
Cucurbitane-type triterpenoids from the tubers of Hemsleya dolichocarpa
收藏切换
PDF
Hua WEI1, 2, *, Yi-han LIU1, Yun-gang TIAN1, Fang-fang XIANG1
Acta Pharmaceutica Sinica | 2018, 53(9) : 1526 - 1531
Less
收藏切换
Acta Pharmaceutica Sinica | 2018, 53(9): 1526-1531
• ORIGINAL ARTICLES •
Cucurbitane-type triterpenoids from the tubers of Hemsleya dolichocarpa
Full
Hua WEI1, 2, *, Yi-han LIU1, Yun-gang TIAN1, Fang-fang XIANG1
Affiliations
  • 1. Tujia Medicine Research Center in Hunan, College of Hunan Province, Jishou University, Jishou 416000, China
  • 2. Key Laboratory of Plant Resources Conservation and Utilization, College of Hunan Province, Jishou University, Jishou 416000, China
Published: 2018-09-12 doi: 10.16438/j.0513-4870.2018-0526
Outline
收藏切换

Seven cucurbitane-type triterpenoids were isolated from the ethanol extract of the tubers of Hemsleya dolichocarpa, with a combination of various chromatographic approaches, including silica gel, Sephadex LH-20, Semi-HPLC and so on. On the basis of spectroscopic data analysis, they were identified as 3β, 11α, 26, 27-tetrahydroxycucurbita-5, 24(E)-diene-3, 26-glucosides (1), scandenogenin D (2), jinfushanencin F (3), scandenoside R3 (4), scandenoside R1 (5), scandenogenin A (6), scandenoside R2 (7). Among them, compound 1 is a new triterpenoid, compound 2 showed remarkable activity against human cancer cell line HeLa with IC50 value of 6.78 μmol·L-1.

Cucurbitaceae  /  Hemsleya genus  /  H.dolichocarpa  /  cucurbitane-type triterpenoids  /  anti-tumor activity
Hua WEI, Yi-han LIU, Yun-gang TIAN, Fang-fang XIANG. Cucurbitane-type triterpenoids from the tubers of Hemsleya dolichocarpa[J]. Acta Pharmaceutica Sinica, 2018 , 53 (9) : 1526 -1531 . DOI: 10.16438/j.0513-4870.2018-0526
Appendix
Less
Year 2018 volume 53 Issue 9
PDF
114
45
Cite this Article
BibTeX
Article Info
doi: 10.16438/j.0513-4870.2018-0526
  • Receive Date：2018-06-06
  • Online Date：2026-01-15
  • Published：2018-09-12
Article Data
Affiliations
History
  • Received：2018-06-06
  • Revised：2018-07-06
Funding
Affiliations
    1. Tujia Medicine Research Center in Hunan, College of Hunan Province, Jishou University, Jishou 416000, China
    2. Key Laboratory of Plant Resources Conservation and Utilization, College of Hunan Province, Jishou University, Jishou 416000, China
References
Share
https://castjournals.cast.org.cn/joweb/yxxb/EN/10.16438/j.0513-4870.2018-0526
Share to
QR

Scan QR to access full text

Cite this article
BibTeX
Citations
表12种不同金属材料的力学参数
科
Family		 属数
Number of
genus		 种数
Number of
species		 占总种数比例
Percentage of
total species (%)		 属
Genus		 种数
Number of
species		 占总种数比例
Percentage of total
species (%)
鹅膏菌科Amanitaceae 2 11 5.26 鹅膏菌属 Amanita 10 4.78
小菇科 Mycenaceae 2 12 5.74 丝盖伞属 Inocybe 5 2.39
多孔菌科 Polyporaceae 8 14 6.70 蜡蘑属 Laccaria 5 2.39
红菇科 Russulaceae 3 23 11.00 小皮伞属 Marasmius 6 2.87
小菇属 Mycena 11 5.26
光柄菇属 Pluteus 5 2.39
红菇属 Russula 17 8.13
栓菌属 Trametes 5 2.39
关闭全屏
  • BibTeX
  • EndNote
  • RefWorks
  • TxT
Links
Articles
Latest Articles
Most Read
Collections
Updates
Events
News
Multimedia
About
About Us
Contact
No. 86 Xueyuan South Road, Haidian District, Beijing
100081
010-62199257
qkjq@cast.org.cn

Copyright © 2025 China Association for Science and Technology. All rights reserved. For all open access content, the relevant licensing terms apply.
Sponsored by the Office of the Leading Group for Cybersecurity and Informatization of CAST, and supported by Science and Technology Review Publishing House